GSM8077692

Dataset: gse255685 • Sample: Z652 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 44.6%ile (≈ Median)
22,353 Genes with score > 0 Group median: 22,381 • 17.6%ile (↓ Low)
0 Median expression score Group median: 0 • 48.9%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

50.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.65
bar=donor   line=cohort median 		2.02 97.3%
FOXO3 Insulin/IGF-1 Signaling 9.85
bar=donor   line=cohort median 		9.99 28.9%
CETP Lipid Metabolism 4.68
bar=donor   line=cohort median 		5.05 9.9%
SIRT6 Sirtuin Family 8.30
bar=donor   line=cohort median 		8.34 37.8%
SIRT1 Sirtuin Family 8.80
bar=donor   line=cohort median 		8.72 65.8%
SIRT3 Sirtuin Family 7.50
bar=donor   line=cohort median 		7.49 52.2%
IGF1R Insulin/IGF-1 Signaling 9.64
bar=donor   line=cohort median 		10.21 7.4%
KLOTHO Anti-aging 2.54
bar=donor   line=cohort median 		2.51 55.4%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 75.8%
IL6 Inflammation 1.38
bar=donor   line=cohort median 		1.16 84.8%
TERT Telomere Maintenance 1.58
bar=donor   line=cohort median 		1.51 65.8%
IRS2 Insulin/IGF-1 Signaling 10.44
bar=donor   line=cohort median 		9.81 81.9%
TP53 Tumor Suppression 8.87
bar=donor   line=cohort median 		8.92 46.1%
SHC1 Signal Transduction 9.33
bar=donor   line=cohort median 		9.35 44.3%
ACE Signal Transduction 4.21
bar=donor   line=cohort median 		4.64 8.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.2 0
2 B2M 17.1 0
3 EEF1A1 17.0 0
4 ACTB 16.4 0
5 MT-CO1 16.4 0
6 HLA-B 16.2 0
7 HLA-C 16.0 0
8 HLA-E 15.8 0
9 TXNIP 15.8 0
10 FTL 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.3
bar=donor   line=cohort median 		14.4 14.2 61.1%
2 S100A9 15.6
bar=donor   line=cohort median 		15.8 15.5 53.2%
3 IL1B 8.5
bar=donor   line=cohort median 		8.8 9.3 15.9%
4 CXCL8 11.2
bar=donor   line=cohort median 		12.2 11.4 46.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.1 6.1 14.2%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 42.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.7
bar=donor   line=cohort median 		14.3 14.3 77.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 80.5%
9 CD3E 12.1
bar=donor   line=cohort median 		12.1 12.0 71.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.1
bar=donor   line=cohort median 		10.8 10.9 76.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.9
bar=donor   line=cohort median 		12.2 11.7 64.7%
12 GNLY 12.0
bar=donor   line=cohort median 		12.4 12.1 43.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 41.8%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 47.5%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.3 15.2 27.8%
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