GSM8077694

Dataset: gse255685 • Sample: Z656 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 68.6%ile (≈ Median)
22,378 Genes with score > 0 Group median: 22,381 • 50.0%ile (≈ Median)
0 Median expression score Group median: 0 • 53.2%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

48.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.17
bar=donor   line=cohort median 		2.02 74.0%
FOXO3 Insulin/IGF-1 Signaling 10.13
bar=donor   line=cohort median 		9.99 72.9%
CETP Lipid Metabolism 4.77
bar=donor   line=cohort median 		5.05 18.5%
SIRT6 Sirtuin Family 8.52
bar=donor   line=cohort median 		8.34 79.8%
SIRT1 Sirtuin Family 8.81
bar=donor   line=cohort median 		8.72 67.6%
SIRT3 Sirtuin Family 7.16
bar=donor   line=cohort median 		7.49 5.2%
IGF1R Insulin/IGF-1 Signaling 10.12
bar=donor   line=cohort median 		10.21 40.7%
KLOTHO Anti-aging 2.33
bar=donor   line=cohort median 		2.51 22.8%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 50.4%
IL6 Inflammation 1.58
bar=donor   line=cohort median 		1.16 94.8%
TERT Telomere Maintenance 1.46
bar=donor   line=cohort median 		1.51 39.6%
IRS2 Insulin/IGF-1 Signaling 10.28
bar=donor   line=cohort median 		9.81 77.2%
TP53 Tumor Suppression 8.49
bar=donor   line=cohort median 		8.92 7.0%
SHC1 Signal Transduction 9.42
bar=donor   line=cohort median 		9.35 70.1%
ACE Signal Transduction 4.26
bar=donor   line=cohort median 		4.64 13.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.5 0
3 HLA-C 16.7 0
4 EEF1A1 16.6 0
5 ACTB 16.5 0
6 MT-CO1 16.4 0
7 HLA-B 16.3 0
8 S100A9 16.1 0
9 HLA-E 16.1 0
10 MT-RNR1 16.0 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.9
bar=donor   line=cohort median 		14.4 14.2 91.6%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 84.4%
3 IL1B 9.7
bar=donor   line=cohort median 		8.8 9.3 71.9%
4 CXCL8 12.1
bar=donor   line=cohort median 		12.2 11.4 71.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 34.2%
6 FCGR3B 15.8
bar=donor   line=cohort median 		14.7 14.7 99.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.1
bar=donor   line=cohort median 		14.3 14.3 98.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.1
bar=donor   line=cohort median 		10.6 10.4 19.5%
9 CD3E 11.6
bar=donor   line=cohort median 		12.1 12.0 3.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.8 10.9 8.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.2
bar=donor   line=cohort median 		12.2 11.7 79.0%
12 GNLY 12.7
bar=donor   line=cohort median 		12.4 12.1 83.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 41.4%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 52.2%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 72.2%
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