GSM8077695

Dataset: gse255685 • Sample: Z661 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 92.3%ile (↑ High)
22,406 Genes with score > 0 Group median: 22,381 • 80.3%ile (↑ High)
0 Median expression score Group median: 0 • 92.7%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

48.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.29
bar=donor   line=cohort median 		2.02 82.3%
FOXO3 Insulin/IGF-1 Signaling 10.24
bar=donor   line=cohort median 		9.99 86.2%
CETP Lipid Metabolism 5.01
bar=donor   line=cohort median 		5.05 44.6%
SIRT6 Sirtuin Family 8.16
bar=donor   line=cohort median 		8.34 11.7%
SIRT1 Sirtuin Family 8.79
bar=donor   line=cohort median 		8.72 64.7%
SIRT3 Sirtuin Family 7.46
bar=donor   line=cohort median 		7.49 43.2%
IGF1R Insulin/IGF-1 Signaling 10.02
bar=donor   line=cohort median 		10.21 32.8%
KLOTHO Anti-aging 2.08
bar=donor   line=cohort median 		2.51 2.0%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 48.9%
IL6 Inflammation 1.88
bar=donor   line=cohort median 		1.16 98.8%
TERT Telomere Maintenance 1.46
bar=donor   line=cohort median 		1.51 39.3%
IRS2 Insulin/IGF-1 Signaling 10.23
bar=donor   line=cohort median 		9.81 74.0%
TP53 Tumor Suppression 8.53
bar=donor   line=cohort median 		8.92 12.4%
SHC1 Signal Transduction 9.38
bar=donor   line=cohort median 		9.35 59.7%
ACE Signal Transduction 4.44
bar=donor   line=cohort median 		4.64 29.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 17.0 0
3 EEF1A1 17.0 0
4 MT-CO1 16.3 0
5 ACTB 16.2 0
6 HLA-C 16.0 0
7 MT-RNR1 15.9 0
8 HLA-E 15.8 0
9 HLA-B 15.6 0
10 TMSB4X 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.4 14.2 50.7%
2 S100A9 15.2
bar=donor   line=cohort median 		15.8 15.5 27.8%
3 IL1B 8.8
bar=donor   line=cohort median 		8.8 9.3 28.1%
4 CXCL8 13.1
bar=donor   line=cohort median 		12.2 11.4 93.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.6
bar=donor   line=cohort median 		6.1 6.1 78.0%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.7 14.7 69.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.7
bar=donor   line=cohort median 		14.3 14.3 7.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 76.9%
9 CD3E 12.1
bar=donor   line=cohort median 		12.1 12.0 70.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.1
bar=donor   line=cohort median 		10.8 10.9 74.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		12.2 11.7 29.9%
12 GNLY 12.0
bar=donor   line=cohort median 		12.4 12.1 42.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.5 16.4 15.6%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.6 15.3 22.4%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 46.4%
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