GSM8077696

Dataset: gse255685 • Sample: Z664 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 64.0%ile (≈ Median)
22,384 Genes with score > 0 Group median: 22,381 • 59.9%ile (≈ Median)
0 Median expression score Group median: 0 • 51.1%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

58.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.06
bar=donor   line=cohort median 		2.02 56.5%
FOXO3 Insulin/IGF-1 Signaling 10.07
bar=donor   line=cohort median 		9.99 60.4%
CETP Lipid Metabolism 4.69
bar=donor   line=cohort median 		5.05 11.7%
SIRT6 Sirtuin Family 8.60
bar=donor   line=cohort median 		8.34 86.6%
SIRT1 Sirtuin Family 8.73
bar=donor   line=cohort median 		8.72 51.1%
SIRT3 Sirtuin Family 7.55
bar=donor   line=cohort median 		7.49 59.7%
IGF1R Insulin/IGF-1 Signaling 10.00
bar=donor   line=cohort median 		10.21 31.4%
KLOTHO Anti-aging 2.68
bar=donor   line=cohort median 		2.51 72.2%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 59.0%
IL6 Inflammation 1.67
bar=donor   line=cohort median 		1.16 95.9%
TERT Telomere Maintenance 1.55
bar=donor   line=cohort median 		1.51 58.2%
IRS2 Insulin/IGF-1 Signaling 10.20
bar=donor   line=cohort median 		9.81 72.2%
TP53 Tumor Suppression 8.68
bar=donor   line=cohort median 		8.92 25.6%
SHC1 Signal Transduction 9.46
bar=donor   line=cohort median 		9.35 80.5%
ACE Signal Transduction 4.67
bar=donor   line=cohort median 		4.64 52.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 B2M 17.1 0
3 EEF1A1 16.9 0
4 MT-CO1 16.5 0
5 ACTB 16.5 0
6 MT-RNR1 16.3 0
7 HLA-B 16.2 0
8 HLA-C 16.1 0
9 MT-ND4 16.0 0
10 FTL 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.3
bar=donor   line=cohort median 		14.4 14.2 61.5%
2 S100A9 15.6
bar=donor   line=cohort median 		15.8 15.5 55.7%
3 IL1B 8.8
bar=donor   line=cohort median 		8.8 9.3 30.6%
4 CXCL8 12.0
bar=donor   line=cohort median 		12.2 11.4 68.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.1 6.1 18.8%
6 FCGR3B 15.1
bar=donor   line=cohort median 		14.7 14.7 80.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.7
bar=donor   line=cohort median 		14.3 14.3 6.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 74.4%
9 CD3E 12.1
bar=donor   line=cohort median 		12.1 12.0 69.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 48.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.8
bar=donor   line=cohort median 		12.2 11.7 61.1%
12 GNLY 12.2
bar=donor   line=cohort median 		12.4 12.1 60.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 64.0%
17 MT-CO2 15.6
bar=donor   line=cohort median 		15.6 15.3 83.7%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.3 15.2 85.1%
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