GSM8077697

Dataset: gse255685 • Sample: Z665 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 44.3%ile (≈ Median)
22,407 Genes with score > 0 Group median: 22,381 • 81.2%ile (↑ High)
0 Median expression score Group median: 0 • 83.7%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

43.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.27
bar=donor   line=cohort median 		2.02 80.5%
FOXO3 Insulin/IGF-1 Signaling 9.89
bar=donor   line=cohort median 		9.99 35.3%
CETP Lipid Metabolism 4.85
bar=donor   line=cohort median 		5.05 28.1%
SIRT6 Sirtuin Family 7.96
bar=donor   line=cohort median 		8.34 0.9%
SIRT1 Sirtuin Family 8.92
bar=donor   line=cohort median 		8.72 86.6%
SIRT3 Sirtuin Family 7.29
bar=donor   line=cohort median 		7.49 15.2%
IGF1R Insulin/IGF-1 Signaling 9.77
bar=donor   line=cohort median 		10.21 15.2%
KLOTHO Anti-aging 2.32
bar=donor   line=cohort median 		2.51 19.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 41.8%
IL6 Inflammation 2.09
bar=donor   line=cohort median 		1.16 99.5%
TERT Telomere Maintenance 1.73
bar=donor   line=cohort median 		1.51 85.5%
IRS2 Insulin/IGF-1 Signaling 9.89
bar=donor   line=cohort median 		9.81 57.2%
TP53 Tumor Suppression 8.73
bar=donor   line=cohort median 		8.92 29.9%
SHC1 Signal Transduction 9.35
bar=donor   line=cohort median 		9.35 48.6%
ACE Signal Transduction 4.19
bar=donor   line=cohort median 		4.64 7.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 EEF1A1 16.9 0
3 B2M 16.8 0
4 MT-CO1 16.3 0
5 ACTB 16.1 0
6 HLA-C 15.9 0
7 MT-RNR1 15.8 0
8 MT-ND4 15.6 0
9 HLA-E 15.6 0
10 HLA-B 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.4
bar=donor   line=cohort median 		14.4 14.2 12.4%
2 S100A9 14.7
bar=donor   line=cohort median 		15.8 15.5 4.8%
3 IL1B 8.6
bar=donor   line=cohort median 		8.8 9.3 20.3%
4 CXCL8 12.7
bar=donor   line=cohort median 		12.2 11.4 87.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.1 6.1 21.3%
6 FCGR3B 14.3
bar=donor   line=cohort median 		14.7 14.7 21.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 31.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 78.3%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 79.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.6
bar=donor   line=cohort median 		10.8 10.9 17.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		12.2 11.7 77.6%
12 GNLY 13.0
bar=donor   line=cohort median 		12.4 12.1 91.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.5 16.4 31.4%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.6 15.3 43.2%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 43.2%
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