GSM8077700

Dataset: gse255685 • Sample: Z676 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 24.9%ile (↓ Low)
22,363 Genes with score > 0 Group median: 22,381 • 30.5%ile (≈ Median)
0 Median expression score Group median: 0 • 31.7%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.43
bar=donor   line=cohort median 		2.02 90.1%
FOXO3 Insulin/IGF-1 Signaling 10.14
bar=donor   line=cohort median 		9.99 75.8%
CETP Lipid Metabolism 4.56
bar=donor   line=cohort median 		5.05 3.4%
SIRT6 Sirtuin Family 8.63
bar=donor   line=cohort median 		8.34 89.1%
SIRT1 Sirtuin Family 8.33
bar=donor   line=cohort median 		8.72 8.1%
SIRT3 Sirtuin Family 7.27
bar=donor   line=cohort median 		7.49 13.4%
IGF1R Insulin/IGF-1 Signaling 9.76
bar=donor   line=cohort median 		10.21 14.9%
KLOTHO Anti-aging 2.49
bar=donor   line=cohort median 		2.51 48.2%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 60.8%
IL6 Inflammation 1.19
bar=donor   line=cohort median 		1.16 57.5%
TERT Telomere Maintenance 1.38
bar=donor   line=cohort median 		1.51 22.8%
IRS2 Insulin/IGF-1 Signaling 10.60
bar=donor   line=cohort median 		9.81 86.9%
TP53 Tumor Suppression 8.80
bar=donor   line=cohort median 		8.92 40.0%
SHC1 Signal Transduction 9.40
bar=donor   line=cohort median 		9.35 65.4%
ACE Signal Transduction 4.18
bar=donor   line=cohort median 		4.64 7.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.3 0
3 EEF1A1 17.0 0
4 ACTB 16.8 0
5 MT-CO1 16.6 0
6 HLA-C 16.5 0
7 FTL 16.2 0
8 HLA-B 16.2 0
9 MT-RNR1 16.2 0
10 HLA-E 16.1 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.5
bar=donor   line=cohort median 		14.4 14.2 72.9%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 82.6%
3 IL1B 8.3
bar=donor   line=cohort median 		8.8 9.3 9.9%
4 CXCL8 12.2
bar=donor   line=cohort median 		12.2 11.4 76.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 51.4%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 47.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.7
bar=donor   line=cohort median 		14.3 14.3 80.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.6 10.4 34.2%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 34.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 53.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.5
bar=donor   line=cohort median 		12.2 11.7 89.1%
12 GNLY 12.6
bar=donor   line=cohort median 		12.4 12.1 81.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.5 16.4 85.1%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 90.1%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.3 15.2 74.4%
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