GSM8077701

Dataset: gse255685 • Sample: Z677 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 75.4%ile (↑ High)
22,380 Genes with score > 0 Group median: 22,381 • 53.8%ile (≈ Median)
0 Median expression score Group median: 0 • 62.5%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.09
bar=donor   line=cohort median 		2.02 63.3%
FOXO3 Insulin/IGF-1 Signaling 10.17
bar=donor   line=cohort median 		9.99 79.0%
CETP Lipid Metabolism 4.70
bar=donor   line=cohort median 		5.05 13.8%
SIRT6 Sirtuin Family 8.36
bar=donor   line=cohort median 		8.34 55.0%
SIRT1 Sirtuin Family 8.64
bar=donor   line=cohort median 		8.72 41.0%
SIRT3 Sirtuin Family 7.44
bar=donor   line=cohort median 		7.49 39.6%
IGF1R Insulin/IGF-1 Signaling 10.09
bar=donor   line=cohort median 		10.21 38.5%
KLOTHO Anti-aging 2.21
bar=donor   line=cohort median 		2.51 10.2%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 72.6%
IL6 Inflammation 1.45
bar=donor   line=cohort median 		1.16 89.8%
TERT Telomere Maintenance 1.49
bar=donor   line=cohort median 		1.51 45.7%
IRS2 Insulin/IGF-1 Signaling 10.17
bar=donor   line=cohort median 		9.81 71.5%
TP53 Tumor Suppression 8.66
bar=donor   line=cohort median 		8.92 22.0%
SHC1 Signal Transduction 9.40
bar=donor   line=cohort median 		9.35 66.1%
ACE Signal Transduction 4.82
bar=donor   line=cohort median 		4.64 67.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.1 0
3 EEF1A1 17.0 0
4 ACTB 16.6 0
5 MT-CO1 16.4 0
6 HLA-C 16.4 0
7 MT-RNR1 16.2 0
8 HLA-B 16.2 0
9 FTL 16.0 0
10 HLA-E 16.0 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.1
bar=donor   line=cohort median 		14.4 14.2 46.4%
2 S100A9 15.6
bar=donor   line=cohort median 		15.8 15.5 53.9%
3 IL1B 8.2
bar=donor   line=cohort median 		8.8 9.3 8.4%
4 CXCL8 13.2
bar=donor   line=cohort median 		12.2 11.4 94.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 57.5%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 38.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 66.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.6 10.4 62.2%
9 CD3E 12.1
bar=donor   line=cohort median 		12.1 12.0 73.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 41.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		12.2 11.7 75.8%
12 GNLY 12.6
bar=donor   line=cohort median 		12.4 12.1 80.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 45.3%
17 MT-CO2 15.6
bar=donor   line=cohort median 		15.6 15.3 80.1%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.3 15.2 85.8%
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