GSM8077702

Dataset: gse255685 • Sample: Z678 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 84.1%ile (↑ High)
22,444 Genes with score > 0 Group median: 22,381 • 96.8%ile (↑ High)
0 Median expression score Group median: 0 • 95.9%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

60.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.37
bar=donor   line=cohort median 		2.02 86.2%
FOXO3 Insulin/IGF-1 Signaling 10.27
bar=donor   line=cohort median 		9.99 87.6%
CETP Lipid Metabolism 4.83
bar=donor   line=cohort median 		5.05 23.8%
SIRT6 Sirtuin Family 8.50
bar=donor   line=cohort median 		8.34 77.2%
SIRT1 Sirtuin Family 8.44
bar=donor   line=cohort median 		8.72 15.2%
SIRT3 Sirtuin Family 7.47
bar=donor   line=cohort median 		7.49 47.5%
IGF1R Insulin/IGF-1 Signaling 10.48
bar=donor   line=cohort median 		10.21 81.2%
KLOTHO Anti-aging 2.31
bar=donor   line=cohort median 		2.51 18.5%
APOC3 Lipid Metabolism -2.08
bar=donor   line=cohort median 		-2.11 94.8%
IL6 Inflammation 1.24
bar=donor   line=cohort median 		1.16 65.1%
TERT Telomere Maintenance 1.59
bar=donor   line=cohort median 		1.51 67.9%
IRS2 Insulin/IGF-1 Signaling 10.49
bar=donor   line=cohort median 		9.81 83.0%
TP53 Tumor Suppression 8.52
bar=donor   line=cohort median 		8.92 11.3%
SHC1 Signal Transduction 9.48
bar=donor   line=cohort median 		9.35 82.3%
ACE Signal Transduction 4.85
bar=donor   line=cohort median 		4.64 71.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 B2M 17.0 0
2 MT-RNR2 17.0 0
3 EEF1A1 16.7 0
4 ACTB 16.5 0
5 HLA-C 16.2 0
6 MT-CO1 16.1 0
7 HLA-E 15.9 0
8 HLA-B 15.9 0
9 CSF3R 15.7 0
10 S100A9 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.3
bar=donor   line=cohort median 		14.4 14.2 58.2%
2 S100A9 15.7
bar=donor   line=cohort median 		15.8 15.5 66.5%
3 IL1B 8.7
bar=donor   line=cohort median 		8.8 9.3 23.8%
4 CXCL8 12.4
bar=donor   line=cohort median 		12.2 11.4 81.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.4
bar=donor   line=cohort median 		6.1 6.1 4.5%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.7 14.7 50.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.2
bar=donor   line=cohort median 		14.3 14.3 40.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.6 10.4 47.8%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 26.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		10.8 10.9 62.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.5
bar=donor   line=cohort median 		12.2 11.7 34.2%
12 GNLY 11.9
bar=donor   line=cohort median 		12.4 12.1 35.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.1
bar=donor   line=cohort median 		16.5 16.4 2.7%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.6 15.3 24.2%
18 MT-ND1 14.8
bar=donor   line=cohort median 		15.3 15.2 6.3%
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