GSM8077703

Dataset: gse255685 • Sample: Z681 • Status: Healthy control
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 85.5%ile (↑ High)
22,406 Genes with score > 0 Group median: 22,381 • 80.3%ile (↑ High)
0 Median expression score Group median: 0 • 93.7%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

40.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.40
bar=donor   line=cohort median 		2.02 87.3%
FOXO3 Insulin/IGF-1 Signaling 9.70
bar=donor   line=cohort median 		9.99 14.2%
CETP Lipid Metabolism 4.59
bar=donor   line=cohort median 		5.05 5.6%
SIRT6 Sirtuin Family 8.76
bar=donor   line=cohort median 		8.34 94.4%
SIRT1 Sirtuin Family 8.15
bar=donor   line=cohort median 		8.72 3.1%
SIRT3 Sirtuin Family 7.66
bar=donor   line=cohort median 		7.49 79.8%
IGF1R Insulin/IGF-1 Signaling 9.57
bar=donor   line=cohort median 		10.21 6.3%
KLOTHO Anti-aging 2.31
bar=donor   line=cohort median 		2.51 19.5%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 78.3%
IL6 Inflammation 1.12
bar=donor   line=cohort median 		1.16 38.5%
TERT Telomere Maintenance 1.59
bar=donor   line=cohort median 		1.51 69.4%
IRS2 Insulin/IGF-1 Signaling 9.69
bar=donor   line=cohort median 		9.81 36.7%
TP53 Tumor Suppression 8.63
bar=donor   line=cohort median 		8.92 18.5%
SHC1 Signal Transduction 9.25
bar=donor   line=cohort median 		9.35 16.3%
ACE Signal Transduction 4.57
bar=donor   line=cohort median 		4.64 43.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.2 0
2 B2M 17.3 0
3 EEF1A1 16.9 0
4 MT-CO1 16.9 0
5 MT-RNR1 16.8 0
6 ACTB 16.7 0
7 HLA-C 16.7 0
8 HLA-B 16.2 0
9 S100A9 16.2 0
10 FTL 16.1 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.6
bar=donor   line=cohort median 		14.4 14.2 79.0%
2 S100A9 16.2
bar=donor   line=cohort median 		15.8 15.5 88.0%
3 IL1B 8.7
bar=donor   line=cohort median 		8.8 9.3 24.6%
4 CXCL8 12.9
bar=donor   line=cohort median 		12.2 11.4 91.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 39.6%
6 FCGR3B 15.2
bar=donor   line=cohort median 		14.7 14.7 86.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.0
bar=donor   line=cohort median 		14.3 14.3 24.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 79.0%
9 CD3E 12.1
bar=donor   line=cohort median 		12.1 12.0 64.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.8 10.9 31.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.6
bar=donor   line=cohort median 		12.2 11.7 91.9%
12 GNLY 13.2
bar=donor   line=cohort median 		12.4 12.1 96.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.9
bar=donor   line=cohort median 		16.5 16.4 97.3%
17 MT-CO2 16.1
bar=donor   line=cohort median 		15.6 15.3 97.3%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 91.2%
◂ Previous Donor Back to Donor List Next Donor ▸