GSM8077707

Dataset: gse255685 • Sample: Z688 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 92.7%ile (↑ High)
22,398 Genes with score > 0 Group median: 22,381 • 72.9%ile (≈ Median)
0 Median expression score Group median: 0 • 57.5%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

47.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.74
bar=donor   line=cohort median 		2.02 99.1%
FOXO3 Insulin/IGF-1 Signaling 9.76
bar=donor   line=cohort median 		9.99 21.3%
CETP Lipid Metabolism 4.43
bar=donor   line=cohort median 		5.05 0.5%
SIRT6 Sirtuin Family 8.85
bar=donor   line=cohort median 		8.34 97.0%
SIRT1 Sirtuin Family 8.12
bar=donor   line=cohort median 		8.72 2.3%
SIRT3 Sirtuin Family 7.56
bar=donor   line=cohort median 		7.49 62.9%
IGF1R Insulin/IGF-1 Signaling 9.65
bar=donor   line=cohort median 		10.21 8.1%
KLOTHO Anti-aging 2.36
bar=donor   line=cohort median 		2.51 28.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 66.9%
IL6 Inflammation 1.28
bar=donor   line=cohort median 		1.16 74.4%
TERT Telomere Maintenance 1.85
bar=donor   line=cohort median 		1.51 94.4%
IRS2 Insulin/IGF-1 Signaling 10.83
bar=donor   line=cohort median 		9.81 94.4%
TP53 Tumor Suppression 8.56
bar=donor   line=cohort median 		8.92 14.5%
SHC1 Signal Transduction 9.27
bar=donor   line=cohort median 		9.35 23.5%
ACE Signal Transduction 4.34
bar=donor   line=cohort median 		4.64 19.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 IGKV3D-11 62.4 0
2 MT-RNR2 17.6 0
3 B2M 17.3 0
4 HLA-C 16.9 0
5 ACTB 16.9 0
6 EEF1A1 16.7 0
7 S100A9 16.5 0
8 MT-CO1 16.4 0
9 HLA-B 16.4 0
10 MT-RNR1 16.2 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.1
bar=donor   line=cohort median 		14.4 14.2 94.8%
2 S100A9 16.5
bar=donor   line=cohort median 		15.8 15.5 95.9%
3 IL1B 8.5
bar=donor   line=cohort median 		8.8 9.3 18.5%
4 CXCL8 11.5
bar=donor   line=cohort median 		12.2 11.4 52.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 26.3%
6 FCGR3B 14.8
bar=donor   line=cohort median 		14.7 14.7 58.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 31.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.6 10.4 58.6%
9 CD3E 11.9
bar=donor   line=cohort median 		12.1 12.0 40.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.3
bar=donor   line=cohort median 		10.8 10.9 5.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.6
bar=donor   line=cohort median 		12.2 11.7 90.5%
12 GNLY 13.2
bar=donor   line=cohort median 		12.4 12.1 94.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 54.3%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.6 15.3 88.4%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 62.9%
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