GSM8077708

Dataset: gse255685 • Sample: Z703 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 76.5%ile (↑ High)
22,427 Genes with score > 0 Group median: 22,381 • 92.8%ile (↑ High)
0 Median expression score Group median: 0 • 87.3%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

52.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.35
bar=donor   line=cohort median 		2.02 85.5%
FOXO3 Insulin/IGF-1 Signaling 10.33
bar=donor   line=cohort median 		9.99 92.3%
CETP Lipid Metabolism 4.80
bar=donor   line=cohort median 		5.05 19.5%
SIRT6 Sirtuin Family 8.55
bar=donor   line=cohort median 		8.34 82.6%
SIRT1 Sirtuin Family 8.46
bar=donor   line=cohort median 		8.72 16.0%
SIRT3 Sirtuin Family 7.57
bar=donor   line=cohort median 		7.49 64.3%
IGF1R Insulin/IGF-1 Signaling 10.14
bar=donor   line=cohort median 		10.21 43.6%
KLOTHO Anti-aging 2.43
bar=donor   line=cohort median 		2.51 39.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 29.9%
IL6 Inflammation 2.36
bar=donor   line=cohort median 		1.16 99.8%
TERT Telomere Maintenance 1.44
bar=donor   line=cohort median 		1.51 33.9%
IRS2 Insulin/IGF-1 Signaling 10.54
bar=donor   line=cohort median 		9.81 85.5%
TP53 Tumor Suppression 8.43
bar=donor   line=cohort median 		8.92 4.1%
SHC1 Signal Transduction 9.38
bar=donor   line=cohort median 		9.35 62.2%
ACE Signal Transduction 4.36
bar=donor   line=cohort median 		4.64 21.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.9 0
2 B2M 17.2 0
3 EEF1A1 17.0 0
4 MT-CO1 16.8 0
5 ACTB 16.7 0
6 MT-RNR1 16.4 0
7 HLA-C 16.4 0
8 HLA-B 16.1 0
9 HLA-E 16.0 0
10 MT-ND4 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		14.4 14.2 36.0%
2 S100A9 15.6
bar=donor   line=cohort median 		15.8 15.5 55.0%
3 IL1B 8.8
bar=donor   line=cohort median 		8.8 9.3 27.4%
4 CXCL8 12.0
bar=donor   line=cohort median 		12.2 11.4 70.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.0
bar=donor   line=cohort median 		6.1 6.1 47.5%
6 FCGR3B 13.8
bar=donor   line=cohort median 		14.7 14.7 4.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.0
bar=donor   line=cohort median 		14.3 14.3 92.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.6 10.4 53.9%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 51.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 51.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.0
bar=donor   line=cohort median 		12.2 11.7 68.6%
12 GNLY 12.0
bar=donor   line=cohort median 		12.4 12.1 40.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.8
bar=donor   line=cohort median 		16.5 16.4 96.6%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 92.3%
18 MT-ND1 15.8
bar=donor   line=cohort median 		15.3 15.2 96.2%
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