GSM8077709

Dataset: gse255685 • Sample: Z705 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 19.5%ile (↓ Low)
22,354 Genes with score > 0 Group median: 22,381 • 18.3%ile (↓ Low)
0 Median expression score Group median: 0 • 23.8%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

48.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.54
bar=donor   line=cohort median 		2.02 94.8%
FOXO3 Insulin/IGF-1 Signaling 9.55
bar=donor   line=cohort median 		9.99 4.5%
CETP Lipid Metabolism 4.91
bar=donor   line=cohort median 		5.05 33.9%
SIRT6 Sirtuin Family 8.48
bar=donor   line=cohort median 		8.34 75.1%
SIRT1 Sirtuin Family 8.81
bar=donor   line=cohort median 		8.72 69.7%
SIRT3 Sirtuin Family 7.43
bar=donor   line=cohort median 		7.49 37.8%
IGF1R Insulin/IGF-1 Signaling 9.68
bar=donor   line=cohort median 		10.21 8.8%
KLOTHO Anti-aging 2.46
bar=donor   line=cohort median 		2.51 44.3%
APOC3 Lipid Metabolism -2.07
bar=donor   line=cohort median 		-2.11 97.3%
IL6 Inflammation 1.30
bar=donor   line=cohort median 		1.16 75.8%
TERT Telomere Maintenance 1.30
bar=donor   line=cohort median 		1.51 7.7%
IRS2 Insulin/IGF-1 Signaling 9.69
bar=donor   line=cohort median 		9.81 37.1%
TP53 Tumor Suppression 8.97
bar=donor   line=cohort median 		8.92 60.0%
SHC1 Signal Transduction 9.36
bar=donor   line=cohort median 		9.35 55.0%
ACE Signal Transduction 4.42
bar=donor   line=cohort median 		4.64 28.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 EEF1A1 17.1 0
3 B2M 17.1 0
4 ACTB 16.7 0
5 MT-CO1 16.6 0
6 HLA-C 16.4 0
7 MT-RNR1 16.0 0
8 FTL 15.9 0
9 HLA-B 15.8 0
10 HLA-E 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.8
bar=donor   line=cohort median 		14.4 14.2 27.1%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 40.0%
3 IL1B 8.8
bar=donor   line=cohort median 		8.8 9.3 29.6%
4 CXCL8 12.3
bar=donor   line=cohort median 		12.2 11.4 77.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 50.0%
6 FCGR3B 13.5
bar=donor   line=cohort median 		14.7 14.7 1.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 67.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.0
bar=donor   line=cohort median 		10.6 10.4 94.1%
9 CD3E 12.4
bar=donor   line=cohort median 		12.1 12.0 92.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.6
bar=donor   line=cohort median 		10.8 10.9 21.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.8
bar=donor   line=cohort median 		12.2 11.7 95.2%
12 GNLY 13.1
bar=donor   line=cohort median 		12.4 12.1 93.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.5 16.4 84.8%
17 MT-CO2 15.6
bar=donor   line=cohort median 		15.6 15.3 81.9%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.3 15.2 76.2%
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