GSM8077710

Dataset: gse255685 • Sample: Z707 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 88.4%ile (↑ High)
22,411 Genes with score > 0 Group median: 22,381 • 85.5%ile (↑ High)
0 Median expression score Group median: 0 • 90.5%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

50.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.82
bar=donor   line=cohort median 		2.02 99.8%
FOXO3 Insulin/IGF-1 Signaling 10.30
bar=donor   line=cohort median 		9.99 91.9%
CETP Lipid Metabolism 4.70
bar=donor   line=cohort median 		5.05 12.4%
SIRT6 Sirtuin Family 9.06
bar=donor   line=cohort median 		8.34 99.8%
SIRT1 Sirtuin Family 8.41
bar=donor   line=cohort median 		8.72 12.4%
SIRT3 Sirtuin Family 7.40
bar=donor   line=cohort median 		7.49 34.6%
IGF1R Insulin/IGF-1 Signaling 10.18
bar=donor   line=cohort median 		10.21 46.4%
KLOTHO Anti-aging 2.15
bar=donor   line=cohort median 		2.51 4.5%
APOC3 Lipid Metabolism -2.07
bar=donor   line=cohort median 		-2.11 97.7%
IL6 Inflammation 1.35
bar=donor   line=cohort median 		1.16 83.7%
TERT Telomere Maintenance 1.64
bar=donor   line=cohort median 		1.51 76.2%
IRS2 Insulin/IGF-1 Signaling 10.50
bar=donor   line=cohort median 		9.81 84.8%
TP53 Tumor Suppression 8.34
bar=donor   line=cohort median 		8.92 1.6%
SHC1 Signal Transduction 9.19
bar=donor   line=cohort median 		9.35 7.7%
ACE Signal Transduction 3.89
bar=donor   line=cohort median 		4.64 0.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.2 0
2 B2M 17.6 0
3 ACTB 17.0 0
4 HLA-C 16.9 0
5 EEF1A1 16.7 0
6 MT-CO1 16.7 0
7 MT-RNR1 16.7 0
8 S100A9 16.6 0
9 HLA-B 16.5 0
10 FTL 16.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.0
bar=donor   line=cohort median 		14.4 14.2 91.9%
2 S100A9 16.6
bar=donor   line=cohort median 		15.8 15.5 97.7%
3 IL1B 8.7
bar=donor   line=cohort median 		8.8 9.3 21.3%
4 CXCL8 12.4
bar=donor   line=cohort median 		12.2 11.4 83.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.5
bar=donor   line=cohort median 		6.1 6.1 70.8%
6 FCGR3B 15.3
bar=donor   line=cohort median 		14.7 14.7 91.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.4
bar=donor   line=cohort median 		14.3 14.3 0.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.7
bar=donor   line=cohort median 		10.6 10.4 81.9%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 61.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.5
bar=donor   line=cohort median 		10.8 10.9 12.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.8
bar=donor   line=cohort median 		12.2 11.7 57.9%
12 GNLY 11.9
bar=donor   line=cohort median 		12.4 12.1 38.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.7
bar=donor   line=cohort median 		16.5 16.4 89.1%
17 MT-CO2 15.9
bar=donor   line=cohort median 		15.6 15.3 95.5%
18 MT-ND1 15.9
bar=donor   line=cohort median 		15.3 15.2 98.0%
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