GSM8077714

Dataset: gse255685 • Sample: Z723 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 48.9%ile (≈ Median)
22,369 Genes with score > 0 Group median: 22,381 • 37.1%ile (≈ Median)
0 Median expression score Group median: 0 • 34.9%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.03
bar=donor   line=cohort median 		2.02 51.4%
FOXO3 Insulin/IGF-1 Signaling 9.94
bar=donor   line=cohort median 		9.99 43.2%
CETP Lipid Metabolism 4.94
bar=donor   line=cohort median 		5.05 37.8%
SIRT6 Sirtuin Family 8.21
bar=donor   line=cohort median 		8.34 19.9%
SIRT1 Sirtuin Family 8.77
bar=donor   line=cohort median 		8.72 61.5%
SIRT3 Sirtuin Family 7.15
bar=donor   line=cohort median 		7.49 4.8%
IGF1R Insulin/IGF-1 Signaling 9.75
bar=donor   line=cohort median 		10.21 14.5%
KLOTHO Anti-aging 2.25
bar=donor   line=cohort median 		2.51 12.4%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 44.6%
IL6 Inflammation 1.32
bar=donor   line=cohort median 		1.16 80.8%
TERT Telomere Maintenance 1.45
bar=donor   line=cohort median 		1.51 38.5%
IRS2 Insulin/IGF-1 Signaling 10.92
bar=donor   line=cohort median 		9.81 96.2%
TP53 Tumor Suppression 8.71
bar=donor   line=cohort median 		8.92 27.8%
SHC1 Signal Transduction 9.50
bar=donor   line=cohort median 		9.35 85.8%
ACE Signal Transduction 4.79
bar=donor   line=cohort median 		4.64 65.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.0 0
2 B2M 17.5 0
3 EEF1A1 16.9 0
4 ACTB 16.7 0
5 MT-CO1 16.5 0
6 HLA-B 16.5 0
7 MT-RNR1 16.4 0
8 TXNIP 16.2 0
9 HLA-E 16.1 0
10 FTL 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.4 14.2 52.5%
2 S100A9 15.7
bar=donor   line=cohort median 		15.8 15.5 61.5%
3 IL1B 9.8
bar=donor   line=cohort median 		8.8 9.3 79.0%
4 CXCL8 11.3
bar=donor   line=cohort median 		12.2 11.4 47.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.3
bar=donor   line=cohort median 		6.1 6.1 63.3%
6 FCGR3B 14.4
bar=donor   line=cohort median 		14.7 14.7 28.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.3 14.3 88.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 74.7%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 57.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 9.8
bar=donor   line=cohort median 		10.8 10.9 0.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.3
bar=donor   line=cohort median 		12.2 11.7 82.3%
12 GNLY 12.5
bar=donor   line=cohort median 		12.4 12.1 75.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 75.1%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 66.5%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.3 15.2 77.6%
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