GSM8077715

Dataset: gse255685 • Sample: Z725 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 42.1%ile (≈ Median)
22,359 Genes with score > 0 Group median: 22,381 • 25.3%ile (≈ Median)
0 Median expression score Group median: 0 • 32.1%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

38.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.21
bar=donor   line=cohort median 		2.02 76.5%
FOXO3 Insulin/IGF-1 Signaling 9.97
bar=donor   line=cohort median 		9.99 46.1%
CETP Lipid Metabolism 4.88
bar=donor   line=cohort median 		5.05 32.4%
SIRT6 Sirtuin Family 8.29
bar=donor   line=cohort median 		8.34 36.4%
SIRT1 Sirtuin Family 8.71
bar=donor   line=cohort median 		8.72 49.6%
SIRT3 Sirtuin Family 7.27
bar=donor   line=cohort median 		7.49 12.7%
IGF1R Insulin/IGF-1 Signaling 9.87
bar=donor   line=cohort median 		10.21 21.7%
KLOTHO Anti-aging 2.44
bar=donor   line=cohort median 		2.51 42.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 36.0%
IL6 Inflammation 0.99
bar=donor   line=cohort median 		1.16 5.9%
TERT Telomere Maintenance 1.52
bar=donor   line=cohort median 		1.51 51.1%
IRS2 Insulin/IGF-1 Signaling 9.87
bar=donor   line=cohort median 		9.81 55.0%
TP53 Tumor Suppression 8.84
bar=donor   line=cohort median 		8.92 42.8%
SHC1 Signal Transduction 9.41
bar=donor   line=cohort median 		9.35 68.6%
ACE Signal Transduction 4.14
bar=donor   line=cohort median 		4.64 5.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 B2M 17.1 0
2 MT-RNR2 17.1 0
3 EEF1A1 16.9 0
4 ACTB 16.7 0
5 MT-CO1 16.3 0
6 HLA-C 16.2 0
7 FTL 15.8 0
8 HLA-E 15.8 0
9 HLA-B 15.7 0
10 TMSB4X 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		14.4 14.2 33.2%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 45.3%
3 IL1B 8.8
bar=donor   line=cohort median 		8.8 9.3 25.3%
4 CXCL8 11.8
bar=donor   line=cohort median 		12.2 11.4 62.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.3
bar=donor   line=cohort median 		6.1 6.1 92.3%
6 FCGR3B 14.3
bar=donor   line=cohort median 		14.7 14.7 22.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 67.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.7
bar=donor   line=cohort median 		10.6 10.4 81.5%
9 CD3E 12.0
bar=donor   line=cohort median 		12.1 12.0 60.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		10.8 10.9 82.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.2
bar=donor   line=cohort median 		12.2 11.7 81.2%
12 GNLY 12.0
bar=donor   line=cohort median 		12.4 12.1 42.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.5 16.4 19.9%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.6 15.3 31.0%
18 MT-ND1 15.0
bar=donor   line=cohort median 		15.3 15.2 21.0%
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