GSM8077716

Dataset: gse255685 • Sample: Z737 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 67.6%ile (≈ Median)
22,396 Genes with score > 0 Group median: 22,381 • 72.0%ile (≈ Median)
0 Median expression score Group median: 0 • 94.8%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

52.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.61
bar=donor   line=cohort median 		2.02 95.9%
FOXO3 Insulin/IGF-1 Signaling 9.69
bar=donor   line=cohort median 		9.99 13.4%
CETP Lipid Metabolism 5.03
bar=donor   line=cohort median 		5.05 48.6%
SIRT6 Sirtuin Family 8.70
bar=donor   line=cohort median 		8.34 91.9%
SIRT1 Sirtuin Family 8.31
bar=donor   line=cohort median 		8.72 6.6%
SIRT3 Sirtuin Family 7.43
bar=donor   line=cohort median 		7.49 37.5%
IGF1R Insulin/IGF-1 Signaling 9.40
bar=donor   line=cohort median 		10.21 2.7%
KLOTHO Anti-aging 2.55
bar=donor   line=cohort median 		2.51 56.5%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 89.4%
IL6 Inflammation 1.26
bar=donor   line=cohort median 		1.16 68.3%
TERT Telomere Maintenance 1.73
bar=donor   line=cohort median 		1.51 86.6%
IRS2 Insulin/IGF-1 Signaling 9.70
bar=donor   line=cohort median 		9.81 38.5%
TP53 Tumor Suppression 8.95
bar=donor   line=cohort median 		8.92 54.7%
SHC1 Signal Transduction 9.26
bar=donor   line=cohort median 		9.35 20.3%
ACE Signal Transduction 4.99
bar=donor   line=cohort median 		4.64 82.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 EEF1A1 17.2 0
3 B2M 17.1 0
4 ACTB 16.7 0
5 HLA-C 16.6 0
6 MT-CO1 16.6 0
7 MT-RNR1 16.4 0
8 FTL 16.1 0
9 HLA-B 16.1 0
10 MT-ND4 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.4 14.2 53.6%
2 S100A9 15.7
bar=donor   line=cohort median 		15.8 15.5 65.4%
3 IL1B 8.0
bar=donor   line=cohort median 		8.8 9.3 3.8%
4 CXCL8 11.4
bar=donor   line=cohort median 		12.2 11.4 50.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.6
bar=donor   line=cohort median 		6.1 6.1 77.2%
6 FCGR3B 14.2
bar=donor   line=cohort median 		14.7 14.7 17.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 70.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.9
bar=donor   line=cohort median 		10.6 10.4 92.7%
9 CD3E 12.4
bar=donor   line=cohort median 		12.1 12.0 94.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.8 10.9 49.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.3
bar=donor   line=cohort median 		12.2 11.7 84.1%
12 GNLY 12.3
bar=donor   line=cohort median 		12.4 12.1 62.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.5 16.4 84.4%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.6 15.3 88.7%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 89.8%
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