GSM8077717

Dataset: gse255685 • Sample: Z741 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 77.2%ile (↑ High)
22,382 Genes with score > 0 Group median: 22,381 • 57.0%ile (≈ Median)
0 Median expression score Group median: 0 • 59.7%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.16
bar=donor   line=cohort median 		2.02 72.6%
FOXO3 Insulin/IGF-1 Signaling 9.91
bar=donor   line=cohort median 		9.99 38.5%
CETP Lipid Metabolism 5.19
bar=donor   line=cohort median 		5.05 69.4%
SIRT6 Sirtuin Family 8.60
bar=donor   line=cohort median 		8.34 87.3%
SIRT1 Sirtuin Family 8.43
bar=donor   line=cohort median 		8.72 14.5%
SIRT3 Sirtuin Family 7.28
bar=donor   line=cohort median 		7.49 13.8%
IGF1R Insulin/IGF-1 Signaling 9.97
bar=donor   line=cohort median 		10.21 29.2%
KLOTHO Anti-aging 2.69
bar=donor   line=cohort median 		2.51 74.7%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 88.4%
IL6 Inflammation 1.14
bar=donor   line=cohort median 		1.16 46.1%
TERT Telomere Maintenance 1.43
bar=donor   line=cohort median 		1.51 31.7%
IRS2 Insulin/IGF-1 Signaling 10.15
bar=donor   line=cohort median 		9.81 71.2%
TP53 Tumor Suppression 8.54
bar=donor   line=cohort median 		8.92 13.8%
SHC1 Signal Transduction 9.55
bar=donor   line=cohort median 		9.35 91.6%
ACE Signal Transduction 4.37
bar=donor   line=cohort median 		4.64 22.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.4 0
3 EEF1A1 17.2 0
4 ACTB 17.0 0
5 HLA-C 16.6 0
6 FTL 16.5 0
7 MT-CO1 16.4 0
8 HLA-E 16.2 0
9 HLA-B 16.1 0
10 MT-RNR1 16.1 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.5
bar=donor   line=cohort median 		14.4 14.2 69.7%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 85.8%
3 IL1B 8.0
bar=donor   line=cohort median 		8.8 9.3 4.5%
4 CXCL8 10.6
bar=donor   line=cohort median 		12.2 11.4 34.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.2
bar=donor   line=cohort median 		6.1 6.1 90.9%
6 FCGR3B 15.3
bar=donor   line=cohort median 		14.7 14.7 89.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.0
bar=donor   line=cohort median 		14.3 14.3 93.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.6 10.4 75.4%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 81.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.6
bar=donor   line=cohort median 		10.8 10.9 19.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		12.2 11.7 75.1%
12 GNLY 11.9
bar=donor   line=cohort median 		12.4 12.1 29.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 34.2%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.6 15.3 78.0%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.3 15.2 78.3%
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