GSM8077718

Dataset: gse255685 • Sample: Z748 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 17.7%ile (↓ Low)
22,370 Genes with score > 0 Group median: 22,381 • 38.9%ile (≈ Median)
0 Median expression score Group median: 0 • 43.5%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

50.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.53
bar=donor   line=cohort median 		2.02 94.4%
FOXO3 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.99 63.3%
CETP Lipid Metabolism 4.66
bar=donor   line=cohort median 		5.05 8.4%
SIRT6 Sirtuin Family 8.86
bar=donor   line=cohort median 		8.34 97.3%
SIRT1 Sirtuin Family 8.42
bar=donor   line=cohort median 		8.72 13.4%
SIRT3 Sirtuin Family 7.18
bar=donor   line=cohort median 		7.49 6.6%
IGF1R Insulin/IGF-1 Signaling 9.90
bar=donor   line=cohort median 		10.21 24.6%
KLOTHO Anti-aging 2.32
bar=donor   line=cohort median 		2.51 21.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 44.3%
IL6 Inflammation 1.45
bar=donor   line=cohort median 		1.16 90.1%
TERT Telomere Maintenance 1.73
bar=donor   line=cohort median 		1.51 85.8%
IRS2 Insulin/IGF-1 Signaling 10.27
bar=donor   line=cohort median 		9.81 76.2%
TP53 Tumor Suppression 8.85
bar=donor   line=cohort median 		8.92 43.6%
SHC1 Signal Transduction 9.34
bar=donor   line=cohort median 		9.35 47.5%
ACE Signal Transduction 4.52
bar=donor   line=cohort median 		4.64 38.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.9 0
2 B2M 17.4 0
3 EEF1A1 17.0 0
4 ACTB 16.9 0
5 HLA-C 16.8 0
6 MT-CO1 16.8 0
7 HLA-B 16.5 0
8 MT-RNR1 16.5 0
9 HLA-E 16.2 0
10 FTL 16.1 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.5
bar=donor   line=cohort median 		14.4 14.2 69.0%
2 S100A9 16.1
bar=donor   line=cohort median 		15.8 15.5 87.3%
3 IL1B 8.4
bar=donor   line=cohort median 		8.8 9.3 14.2%
4 CXCL8 12.4
bar=donor   line=cohort median 		12.2 11.4 83.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.1 6.1 15.6%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.7 14.7 69.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.8
bar=donor   line=cohort median 		14.3 14.3 11.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.7
bar=donor   line=cohort median 		10.6 10.4 85.5%
9 CD3E 12.3
bar=donor   line=cohort median 		12.1 12.0 87.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.5
bar=donor   line=cohort median 		10.8 10.9 13.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.8
bar=donor   line=cohort median 		12.2 11.7 96.2%
12 GNLY 12.8
bar=donor   line=cohort median 		12.4 12.1 88.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.8
bar=donor   line=cohort median 		16.5 16.4 93.7%
17 MT-CO2 15.9
bar=donor   line=cohort median 		15.6 15.3 95.2%
18 MT-ND1 15.6
bar=donor   line=cohort median 		15.3 15.2 91.6%
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