GSM8077721

Dataset: gse255685 • Sample: Z756 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 24.6%ile (↓ Low)
22,360 Genes with score > 0 Group median: 22,381 • 26.0%ile (≈ Median)
0 Median expression score Group median: 0 • 28.1%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

39.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.45
bar=donor   line=cohort median 		2.02 91.2%
FOXO3 Insulin/IGF-1 Signaling 9.63
bar=donor   line=cohort median 		9.99 9.1%
CETP Lipid Metabolism 4.51
bar=donor   line=cohort median 		5.05 1.3%
SIRT6 Sirtuin Family 8.44
bar=donor   line=cohort median 		8.34 68.3%
SIRT1 Sirtuin Family 8.47
bar=donor   line=cohort median 		8.72 17.4%
SIRT3 Sirtuin Family 7.53
bar=donor   line=cohort median 		7.49 57.5%
IGF1R Insulin/IGF-1 Signaling 9.33
bar=donor   line=cohort median 		10.21 1.6%
KLOTHO Anti-aging 2.17
bar=donor   line=cohort median 		2.51 5.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 50.0%
IL6 Inflammation 1.17
bar=donor   line=cohort median 		1.16 55.0%
TERT Telomere Maintenance 1.68
bar=donor   line=cohort median 		1.51 81.5%
IRS2 Insulin/IGF-1 Signaling 9.33
bar=donor   line=cohort median 		9.81 10.6%
TP53 Tumor Suppression 8.88
bar=donor   line=cohort median 		8.92 47.9%
SHC1 Signal Transduction 9.38
bar=donor   line=cohort median 		9.35 60.8%
ACE Signal Transduction 4.47
bar=donor   line=cohort median 		4.64 35.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 17.3 0
3 EEF1A1 17.2 0
4 HLA-C 16.5 0
5 ACTB 16.5 0
6 MT-CO1 16.4 0
7 HLA-B 16.2 0
8 HLA-E 16.0 0
9 MT-RNR1 16.0 0
10 FTL 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.8
bar=donor   line=cohort median 		14.4 14.2 24.6%
2 S100A9 15.3
bar=donor   line=cohort median 		15.8 15.5 31.0%
3 IL1B 8.4
bar=donor   line=cohort median 		8.8 9.3 12.7%
4 CXCL8 11.2
bar=donor   line=cohort median 		12.2 11.4 45.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.4
bar=donor   line=cohort median 		6.1 6.1 4.1%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.7 14.7 66.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.9
bar=donor   line=cohort median 		14.3 14.3 17.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.0
bar=donor   line=cohort median 		10.6 10.4 95.9%
9 CD3E 12.5
bar=donor   line=cohort median 		12.1 12.0 96.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.8 10.9 38.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.6
bar=donor   line=cohort median 		12.2 11.7 90.1%
12 GNLY 12.5
bar=donor   line=cohort median 		12.4 12.1 78.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 45.0%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 61.1%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.3 15.2 73.7%
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