GSM8077722

Dataset: gse255685 • Sample: Z758 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 86.6%ile (↑ High)
22,410 Genes with score > 0 Group median: 22,381 • 84.1%ile (↑ High)
0 Median expression score Group median: 0 • 82.6%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

53.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.97
bar=donor   line=cohort median 		2.02 42.8%
FOXO3 Insulin/IGF-1 Signaling 10.59
bar=donor   line=cohort median 		9.99 98.0%
CETP Lipid Metabolism 4.91
bar=donor   line=cohort median 		5.05 34.6%
SIRT6 Sirtuin Family 8.35
bar=donor   line=cohort median 		8.34 53.2%
SIRT1 Sirtuin Family 8.86
bar=donor   line=cohort median 		8.72 77.2%
SIRT3 Sirtuin Family 7.30
bar=donor   line=cohort median 		7.49 17.0%
IGF1R Insulin/IGF-1 Signaling 10.45
bar=donor   line=cohort median 		10.21 78.0%
KLOTHO Anti-aging 2.67
bar=donor   line=cohort median 		2.51 71.5%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 87.3%
IL6 Inflammation 1.14
bar=donor   line=cohort median 		1.16 43.6%
TERT Telomere Maintenance 1.32
bar=donor   line=cohort median 		1.51 10.9%
IRS2 Insulin/IGF-1 Signaling 11.49
bar=donor   line=cohort median 		9.81 99.8%
TP53 Tumor Suppression 8.54
bar=donor   line=cohort median 		8.92 13.1%
SHC1 Signal Transduction 9.38
bar=donor   line=cohort median 		9.35 63.6%
ACE Signal Transduction 4.25
bar=donor   line=cohort median 		4.64 12.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.1 0
3 EEF1A1 17.0 0
4 ACTB 16.5 0
5 MT-CO1 16.4 0
6 HLA-C 16.2 0
7 FTL 16.2 0
8 MT-RNR1 16.1 0
9 FKBP8 16.0 0
10 TXNIP 16.0 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		14.4 14.2 31.4%
2 S100A9 15.4
bar=donor   line=cohort median 		15.8 15.5 41.8%
3 IL1B 8.3
bar=donor   line=cohort median 		8.8 9.3 11.3%
4 CXCL8 10.8
bar=donor   line=cohort median 		12.2 11.4 40.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.3
bar=donor   line=cohort median 		6.1 6.1 62.9%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.7 14.7 41.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.9
bar=donor   line=cohort median 		14.3 14.3 18.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.6 10.4 27.8%
9 CD3E 11.7
bar=donor   line=cohort median 		12.1 12.0 13.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		10.8 10.9 77.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.0
bar=donor   line=cohort median 		12.2 11.7 69.4%
12 GNLY 12.1
bar=donor   line=cohort median 		12.4 12.1 45.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.5 16.4 52.9%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.6 15.3 64.7%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.3 15.2 42.8%
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