GSM8077723

Dataset: gse255685 • Sample: Z761 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 58.6%ile (≈ Median)
22,367 Genes with score > 0 Group median: 22,381 • 34.8%ile (≈ Median)
0 Median expression score Group median: 0 • 33.9%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

55.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.15
bar=donor   line=cohort median 		2.02 70.4%
FOXO3 Insulin/IGF-1 Signaling 9.85
bar=donor   line=cohort median 		9.99 29.6%
CETP Lipid Metabolism 4.98
bar=donor   line=cohort median 		5.05 42.5%
SIRT6 Sirtuin Family 8.93
bar=donor   line=cohort median 		8.34 98.4%
SIRT1 Sirtuin Family 8.41
bar=donor   line=cohort median 		8.72 12.0%
SIRT3 Sirtuin Family 7.65
bar=donor   line=cohort median 		7.49 78.7%
IGF1R Insulin/IGF-1 Signaling 9.83
bar=donor   line=cohort median 		10.21 18.1%
KLOTHO Anti-aging 2.52
bar=donor   line=cohort median 		2.51 52.2%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 87.6%
IL6 Inflammation 1.43
bar=donor   line=cohort median 		1.16 89.1%
TERT Telomere Maintenance 1.79
bar=donor   line=cohort median 		1.51 90.1%
IRS2 Insulin/IGF-1 Signaling 10.30
bar=donor   line=cohort median 		9.81 78.3%
TP53 Tumor Suppression 8.74
bar=donor   line=cohort median 		8.92 31.0%
SHC1 Signal Transduction 9.20
bar=donor   line=cohort median 		9.35 8.8%
ACE Signal Transduction 4.58
bar=donor   line=cohort median 		4.64 46.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 B2M 17.5 0
3 EEF1A1 17.1 0
4 ACTB 17.0 0
5 HLA-C 17.0 0
6 HLA-B 16.8 0
7 S100A9 16.6 0
8 MT-CO1 16.5 0
9 FTL 16.3 0
10 MT-RNR1 16.3 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.1
bar=donor   line=cohort median 		14.4 14.2 93.7%
2 S100A9 16.6
bar=donor   line=cohort median 		15.8 15.5 97.3%
3 IL1B 8.4
bar=donor   line=cohort median 		8.8 9.3 12.0%
4 CXCL8 12.1
bar=donor   line=cohort median 		12.2 11.4 72.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 52.9%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.7 14.7 69.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.6
bar=donor   line=cohort median 		14.3 14.3 4.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.8
bar=donor   line=cohort median 		10.6 10.4 90.5%
9 CD3E 12.2
bar=donor   line=cohort median 		12.1 12.0 83.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.3
bar=donor   line=cohort median 		10.8 10.9 86.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.9
bar=donor   line=cohort median 		12.2 11.7 64.0%
12 GNLY 11.9
bar=donor   line=cohort median 		12.4 12.1 31.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.5 16.4 57.5%
17 MT-CO2 15.8
bar=donor   line=cohort median 		15.6 15.3 89.8%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.3 15.2 83.3%
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