Tissues

The whole brain refers to the entire encephalon, encompassing all major divisions: cerebrum (cerebral hemispheres), cerebellum, and brainstem (midbrain, pons, medulla). It is the central organ of the nervous system, responsible for integrating sensory information, generating thoughts and emotions, coordinating all voluntary and involuntary bodily functions, and enabling consciousness. It is protected by the skull and meninges.

This complex refers to the functional unit of the posterior eye, comprising the neural retina and the underlying retinal pigment epithelium (RPE). The neural retina detects and processes light, while the RPE provides critical metabolic support, waste removal, and light absorption. Their intimate structural and functional relationship is essential for normal vision; diseases often involve both layers.

Peripheral Blood Mononuclear Cells (PBMCs) are a population of blood cells with a single, round nucleus, isolated from peripheral blood. This mixed cell population primarily includes lymphocytes (T cells, B cells, NK cells) and monocytes. They are a critical component of the immune system and are widely used in research and diagnostics for immunophenotyping, functional assays, and genetic studies.

The spleen is the largest secondary lymphoid organ, located in the left upper abdomen. It filters blood, removing old or damaged red blood cells and platelets, and captures blood-borne pathogens. Its white pulp contains immune cells (lymphocytes, macrophages) that mount immune responses. The red pulp is responsible for RBC filtration and storage. It is a key site for antibody production and immune surveillance.

The heart is a muscular organ that functions as the central pump of the circulatory system. It has four chambers: two atria (receiving chambers) and two ventricles (pumping chambers). Through coordinated, rhythmic contractions (the cardiac cycle), it pumps deoxygenated blood to the lungs via the pulmonary circuit and oxygenated blood to the rest of the body via the systemic circuit. Its own blood supply comes from the coronary arteries.

The liver is the largest internal organ and a metabolic powerhouse located in the upper right abdomen. It performs over 500 vital functions, including detoxification of metabolites, protein synthesis, production of biochemicals for digestion (bile), glycogen storage, regulation of blood glucose, synthesis of plasma proteins (e.g., albumin), and breakdown of old red blood cells. It has a remarkable capacity for regeneration.

The testes (singular: testis) are the male primary gonads, housed in the scrotum. They have two primary functions: spermatogenesis, the production of spermatozoa in the seminiferous tubules; and steroidogenesis, the secretion of androgens, primarily testosterone, by Leydig cells. Temperature regulation in the scrotum is essential for normal spermatogenesis. Testosterone drives male secondary sexual characteristics and reproductive function.

The ovaries are the female primary gonads, located in the pelvic cavity. They have two key functions: gametogenesis, the production and release of oocytes (eggs) through ovulation; and steroidogenesis, the secretion of the sex hormones estrogen and progesterone. These hormones regulate the menstrual cycle, support pregnancy, and maintain female secondary sexual characteristics. The ovaries contain a finite number of follicles at birth.

Skeletal muscle is a type of striated muscle tissue attached to bones by tendons. It is under voluntary control via the somatic nervous system and is responsible for all locomotion, posture, and voluntary movements. Each muscle fiber is multinucleated and contains highly organized myofibrils with sarcomeres, the contractile units. It also functions as a major metabolic organ and an endocrine tissue, secreting myokines.

The kidneys are paired, bean-shaped organs located retroperitoneally in the upper abdominal area. They are the body's primary filtration system, removing waste products and excess ions from blood to form urine. They critically regulate blood volume, pressure, pH, and electrolyte balance (e.g., sodium, potassium). They also produce hormones: erythropoietin (stimulates RBC production) and renin (regulates blood pressure).

The skin is the body's largest organ, forming a protective barrier against the external environment. It has two main layers: the epidermis (outer, keratinized stratified squamous epithelium) and the underlying dermis (dense connective tissue with blood vessels, nerves, appendages). Functions include thermoregulation, sensation (touch, pain, temperature), protection from pathogens and UV radiation, synthesis of vitamin D, and preventing excessive water loss.