⚙ How is this computed? Methods: Correlation Analysis
Longevity · Real single-cell summary

Longevity signature by Cell Type

Nervous system illustration
sys01 · Nervous system
System introduction

Nervous system

The nervous system is the body's master control and communication network. It is divided into the central nervous system (CNS: brain and spinal cord) and the peripheral nervous system (PNS: nerves and ganglia). Using electrical and chemical signals, it integrates sensory input, processes information, and coordinates voluntary and involuntary responses. It enables thought, memory, emotion, perception, and regulates all bodily functions through motor output to muscles and glands.

Source: LACA body-system catalog

Observed descriptive scores for the predefined 15-gene longevity signature in SP121's selected system. Values are read from the published system payload.

SP121 · Nervous system255,483 cells31 cell types
Download summary CSV →Open source analysis →
0.06088Overall mean score
0.05907Overall median
0.1262895th percentile
88.77%Cells with score > 0
Muller cellsHighest observed mean score
Selected system

Cell-type summary

Filter by system or cell type. “Positive” means score greater than zero; it is not a p-value or enrichment call.

RankCell typeCellsMean scorePositive cellsMaximumSampling note
Method & provenance

Dataset contract

Equal-weight species-calibrated score

mean(clip(matrix_value / species_positive_q99, 0, 1))

  • Each mapped gene is scaled by its 99th percentile among positive cells in the complete source-species H5AD.
  • The same 15 mapped genes and SP121 species calibration are used for every system.
  • The score is descriptive relative expression on a 0–1 scale.

Pinned analyzed release

Release: r20260808-v4
Source file: SP121.h5ad
Cell-type key: laca_curated_celltype_v3
Generated: 2026-08-07T17:18:33.318605+00:00

Raw JSON →