⚙ How is this computed? Methods: Correlation Analysis
Longevity · Real single-cell summary

Longevity signature by Cell Type

Immune system illustration
sys02 · Immune system
System introduction

Immune system

The immune system is a complex defense network that protects the body from pathogens like bacteria, viruses, and fungi, as well as from abnormal cells. It consists of innate (non-specific, immediate) and adaptive (specific, memory-based) components. Key cells include lymphocytes (B and T cells), phagocytes (macrophages, neutrophils), and antigen-presenting cells. It functions via physical barriers, immune surveillance, targeted attacks, and the production of antibodies and cytokines to maintain health and homeostasis.

Source: LACA body-system catalog

Observed descriptive scores for the predefined 15-gene longevity signature in SP121's selected system. Values are read from the published system payload.

SP121 · Immune system376,788 cells23 cell types
0.06336Overall mean score
0.05573Overall median
0.1575895th percentile
82.33%Cells with score > 0
NeutrophilsHighest observed mean score
Selected system

Cell-type summary

Filter by system or cell type. “Positive” means score greater than zero; it is not a p-value or enrichment call.

RankCell typeCellsMean scorePositive cellsMaximumSampling note
Method & provenance

Dataset contract

Equal-weight species-calibrated score

mean(clip(matrix_value / species_positive_q99, 0, 1))

  • Each mapped gene is scaled by its 99th percentile among positive cells in the complete source-species H5AD.
  • The same 15 mapped genes and SP121 species calibration are used for every system.
  • The score is descriptive relative expression on a 0–1 scale.

Pinned analyzed release

Release: r20260808-v4
Source file: SP121.h5ad
Cell-type key: laca_curated_celltype_v3
Generated: 2026-08-07T17:18:36.695192+00:00