Longevity signature by Cell Type

System introduction

Reproductive system

The reproductive system enables the production of offspring. It differs significantly between males and females. The male system (testes, ducts, accessory glands, penis) produces and delivers sperm. The female system (ovaries, fallopian tubes, uterus, vagina) produces oocytes (eggs), supports fertilization, and nurtures fetal development. This system is regulated by sex hormones (testosterone, estrogen, progesterone) and is crucial for genetic continuity and the survival of the species.

Source: LACA body-system catalog

Observed descriptive scores for the predefined 15-gene longevity signature in SP121's selected system. Values are read from the published system payload.

SP121 · Reproductive system90,020 cells25 cell types

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0.07848Overall mean score

0.07592Overall median

0.1576395th percentile

93.76%Cells with score > 0

Glandular cellsHighest observed mean score

Selected system

Cell-type summary

Filter by system or cell type. “Positive” means score greater than zero; it is not a p-value or enrichment call.

Search system or cell type

Minimum cells

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Rank	Cell type	Cells	Mean score	Positive cells	Maximum	Sampling note

Method & provenance

Dataset contract

Equal-weight species-calibrated score

mean(clip(matrix_value / species_positive_q99, 0, 1))

Each mapped gene is scaled by its 99th percentile among positive cells in the complete source-species H5AD.
The same 15 mapped genes and SP121 species calibration are used for every system.
The score is descriptive relative expression on a 0–1 scale.

Pinned analyzed release

Release: r20260808-v4
Source file: SP121.h5ad
Cell-type key: laca_curated_celltype_v3
Generated: 2026-08-07T17:18:40.303875+00:00

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