TFs Analyzed
13
Transcription factors profiled
Exploratory Modules Available
Analysis Results SP2038
Published legacy analysis modules for the selected page.
๐ Species Level
No validated Atlas analysis release is published for this page.
Validated exploratory / stratified sample.
Artifact and provenance checks passed for the linked advanced-module package.
These tabs use a deterministic tissue x cell-type stratified sample
(n=1,762,
seed=20260808) and are descriptive cell-level analyses,
not donor-level inference. Cell communication, species-wide trajectory, and age association remain not computed.
Cell Communication
Not computed
TF Associations
Exploratory
Co-expression
Exploratory
Trajectory
Not computed
Marker Ranking
Exploratory
GO / KEGG
Not computed
ToppGene
Not computed
Motif
Not computed
Metabolism
Exploratory
Disease
Exploratory
Drug Analysis
Exploratory
Full Report
Exploratory TF-Target AssociationsPearson associations in the stratified sample; not causal regulatory inference
๐๏ธ
๐
TF-Target Pairs
44
Thresholded Pearson associations
Top TF Association Counts
E2F1
8 associations
ETS2
6 associations
EYA1
4 associations
IRF1
7 associations
MLXIPL
3 associations
RUNX1
4 associations
RUNX2
6 associations
SOX11
2 associations
ZEB2
4 associations
TF Activity Heatmap
Z-score normalized TF expression across cell populations.
Exploratory TF-Target Association Network
Pearson TF-target associations in the stratified sample; not a causal regulatory network.
Gene Co-expression NetworkExpression-correlation modules in the stratified sample; descriptive only
๐ฆ
Modules Identified
30
Co-expression gene modules
๐งฌ
Genes Analyzed
2,000
Highly variable genes
Module Dendrogram
Hierarchical clustering of expression correlations in the stratified sample.
Module-Cell Type Association
Module eigengene activity across cell types.
Descriptive Marker RankingCell-type marker ranking in sampled cells; not donor-level differential inference
๐
Ranked Marker Rows
400
Cell-level descriptive thresholds; no independent donor replicates
๐ท๏ธ
Cell Types Compared
8
Cell populations analyzed
Marker Ranking Volcano Plot
Cell-level descriptive marker ranking; not donor-level differential inference.
Marker Gene Heatmap
Z-score normalized expression of top marker genes per cell type.
๐ Top Marker Genes
| names | scores | logfoldchanges | pvals | pvals_adj | pct_nz_group | pct_nz_reference | cell_type |
|---|---|---|---|---|---|---|---|
| GRIK1 | 17.5754 | 4.7067 | 0 | 0 | 0.7333 | 0.1806 | BP |
| OPN4 | 15.8634 | 4.6696 | 0 | 0 | 0.64 | 0.1074 | BP |
| TAFA4 | 7.9141 | 3.7468 | 0 | 0 | 0.3333 | 0.0547 | BP |
| SLC12A7 | 16.0191 | 3.6763 | 0 | 0 | 0.7067 | 0.2189 | BP |
| NETO1 | 13.6939 | 3.6093 | 0 | 0 | 0.61 | 0.1765 | BP |
| ZNF385B | 16.1081 | 3.5772 | 0 | 0 | 0.72 | 0.2312 | BP |
| KCND2 | 12.2708 | 3.5204 | 0 | 0 | 0.5567 | 0.156 | BP |
| PRKCA | 11.0788 | 3.4835 | 0 | 0 | 0.4967 | 0.13 | BP |
| KCNH6 | 9.4007 | 3.3403 | 0 | 0 | 0.4167 | 0.0958 | BP |
| PCP2 | 4.8147 | 3.1118 | 0 | 0.0001 | 0.2133 | 0.0404 | BP |
| CNGB3 | 21.0746 | 6.5275 | 0 | 0 | 0.7933 | 0.0431 | Cone |
| PDE6C | 20.4893 | 6.4225 | 0 | 0 | 0.7733 | 0.0472 | Cone |
Showing top 12 rows
Metabolism AnalysisCurated metabolic gene-set expression scores; descriptive only
๐งช
Pathways Scored
12
Metabolic pathway gene sets tested
โ
Pathways Detected
11
Pathways with genes expressed in data
๐ท๏ธ
Cell Types Analyzed
9
Cell populations scored
Top Metabolic Pathways
Metabolic Pathway Heatmap
Curated metabolic gene-set expression scores across sampled cell types.
Top Metabolic Activities
Top pathway-cell type combinations ranked by activity score. Dot size: genes detected.
Disease AssociationCurated disease-gene set overlap; descriptive only
๐ฌ
Diseases Tested
15
Disease categories analyzed
โ
Significant Associations
3
Cell type-disease links (adj. p < 0.05)
Top Associated Diseases
Disease Association Heatmap
Curated disease-gene set overlap across sampled cell types; descriptive only.
Top Disease Associations
Dot size: overlap genes. Color: significance.
Drug Target AnalysisCurated drug-target expression matching; descriptive only
๐
Drugs Screened
18
Drug compounds evaluated
๐ฏ
Drugs with Targets
5
Drugs with target genes detected in data
๐ท๏ธ
Cell Types Analyzed
9
Cell populations scored
Top Associated Drugs
Drug Target Expression Heatmap
Curated drug-target expression scores across sampled cell types; descriptive only.
Top DrugโCell Type Associations
Dot size: % cells expressing targets. Color: number of targets detected.
๐ DrugโCell Type Scores
| drug | cell_type | category | indication | targets_detected | targets_total | mean_target_expr | pct_cells_expressing | deg_overlap | target_genes |
|---|---|---|---|---|---|---|---|---|---|
| Imatinib | Other | Kinase inhibitor | CML / GIST | 1 | 5 | 0.06 | 2 | 0 | PDGFRA |
| Imatinib | GabaAC | Kinase inhibitor | CML / GIST | 1 | 5 | 0.0321 | 1.3333 | 0 | PDGFRA |
| Imatinib | Cone | Kinase inhibitor | CML / GIST | 1 | 5 | 0.0241 | 1.3333 | 0 | PDGFRA |
| Imatinib | RGC | Kinase inhibitor | CML / GIST | 1 | 5 | 0.0075 | 0.3333 | 0 | PDGFRA |
| Imatinib | BP | Kinase inhibitor | CML / GIST | 1 | 5 | 0.0242 | 1 | 0 | PDGFRA |
| Imatinib | GlyAC | Kinase inhibitor | CML / GIST | 1 | 5 | 0.0436 | 2.2472 | 0 | PDGFRA |
| Imatinib | MG | Kinase inhibitor | CML / GIST | 1 | 5 | 0.1931 | 9.0909 | 0 | PDGFRA |
| Imatinib | HC | Kinase inhibitor | CML / GIST | 1 | 5 | 0 | 0 | 0 | PDGFRA |
| Imatinib | Rod | Kinase inhibitor | CML / GIST | 1 | 5 | 0 | 0 | 0 | PDGFRA |
| Methotrexate | Other | Antimetabolite | RA / Cancer | 1 | 3 | 0.0095 | 0.3333 | 0 | DHFR |
| Methotrexate | GabaAC | Antimetabolite | RA / Cancer | 1 | 3 | 0.0143 | 0.6667 | 0 | DHFR |
| Methotrexate | Cone | Antimetabolite | RA / Cancer | 1 | 3 | 0.0157 | 1 | 0 | DHFR |
Showing top 12 rows ยท Download full table above
Exploratory Analysis FilesValidated module artifacts and individual downloads
Exploratory Result Files
Use the validated per-module links below. The general Atlas ZIP endpoint is not presented as containing this linked exploratory package.
Share Results
Use this permanent link to share these analysis results:
analysis.php?SP_ID=SP2038
๐ Available Result Files
| Analysis | File | Type | Action |
|---|---|---|---|
| TF Associations | grn_tf_heatmap.png | Figure (PNG) | ๐ View |
| TF Associations | grn_network.png | Figure (PNG) | ๐ View |
| TF Associations | grn_tf_activity.csv | Data (CSV) | ๐ฅ Download |
| TF Associations | grn_tf_targets.csv | Data (CSV) | ๐ฅ Download |
| Co-expression | coexp_dendrogram.png | Figure (PNG) | ๐ View |
| Co-expression | coexp_module_heatmap.png | Figure (PNG) | ๐ View |
| Co-expression | coexp_modules.csv | Data (CSV) | ๐ฅ Download |
| Co-expression | coexp_eigengenes.csv | Data (CSV) | ๐ฅ Download |
| Marker Ranking | deg_volcano.png | Figure (PNG) | ๐ View |
| Marker Ranking | deg_marker_heatmap.png | Figure (PNG) | ๐ View |
| Marker Ranking | deg_top_markers.csv | Data (CSV) | ๐ฅ Download |
| Marker Ranking | deg_significant.csv | Data (CSV) | ๐ฅ Download |
| Marker Ranking | deg_all_results.csv | Data (CSV) | ๐ฅ Download |
| Metabolism | metabolism_heatmap.png | Figure (PNG) | ๐ View |
| Metabolism | metabolism_dotplot.png | Figure (PNG) | ๐ View |
| Metabolism | metabolism_scores.csv | Data (CSV) | ๐ฅ Download |
| Disease | disease_heatmap.png | Figure (PNG) | ๐ View |
| Disease | disease_dotplot.png | Figure (PNG) | ๐ View |
| Disease | disease_enrichment.csv | Data (CSV) | ๐ฅ Download |
| Drug Analysis | drug_heatmap.png | Figure (PNG) | ๐ View |
| Drug Analysis | drug_dotplot.png | Figure (PNG) | ๐ View |
| Drug Analysis | drug_scores.csv | Data (CSV) | ๐ฅ Download |
| Report | SP2038_summary.json | Summary (JSON) | ๐ฅ Download |