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Species
Fruit fly
Drosophila melanogaster
Insects
Species Overview
The common fruit fly Drosophila melanogaster is the premier invertebrate model organism in genetics, development, and aging research. Adults are about 2-3 mm with reddish eyes and a tan-brown body; males are smaller with a dark posterior tip. Its four chromosome pairs carry roughly 14,000 protein-coding genes, and over 60% of human disease genes have clear fly homologs. Many conserved lifespan and aging pathways (insulin/IGF-1, TOR, sirtuins, AMPK) were first characterized or deeply explored in this species. Females lay hundreds of eggs and a complete life cycle takes about 10 days at 25โ. The short 60-80 day adult lifespan and powerful genetic toolkits (Gal4/UAS, CRISPR, balancer chromosomes) make Drosophila a central workhorse for high-throughput longevity screens, identifying aging modifiers such as InR/daf-2, TOR, methuselah, and Indy.
Integrated UMAP Atlas & Gene Explorer
Provisional atlas export
This view is a provisional export of the LACA whole-fly aging compendium (derived from public Drosophila aging atlas resources; genotypes DGRP-551 and w1118): 151,382 cells across 18 tissues, BBKNN batch-corrected at the LACA level and subsampled to ~10,000 cells per tissue. Cell-type labels use the original study annotations, mapped to the LACA standard vocabulary where possible; unmapped labels (including numeric cluster IDs) are shown as-is. Dataset metadata alignment is in progress.
151,382 cells ยท whole-fly aging compendium Loading UMAP for Fruit flyโฆ
Cell Distribution โ WebGL
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Cell Types
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Tissues
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Systems
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Samples
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Cell Types
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Biological System Atlas2Systems
View by Tissue
Tissue-Level Cell Distribution4Tissues
View by Cell Type
Cellular Composition Explorer91Cell Types
adult brain cell body glial cell
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adult brain perineurial glial cell
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adult fat body_head
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adult lamina epithelial/marginal glial cell
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adult optic chiasma glial cell
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adult reticular neuropil associated glial cell_head
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alpha'/beta' Kenyon cell
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alpha/beta Kenyon cell
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antennal lobe projection neuron
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auditory sensory neuron
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centrifugal neuron C2
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centrifugal neuron C3
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columnar neuron T1
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cone cell
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distal medullary amacrine neuron Dm10
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distal medullary amacrine neuron Dm12
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distal medullary amacrine neuron Dm3
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distal medullary amacrine neuron Dm8
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distal medullary amacrine neuron Dm9
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dopaminergic PAM neuron
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ensheathing glial cell
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epithelial cell_head
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gamma Kenyon cell
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hemocyte_head
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Johnston organ neuron
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Kenyon cell
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lamina intrinsic amacrine neuron Lai
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lamina monopolar neuron L1
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lamina monopolar neuron L2
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lamina monopolar neuron L3
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lamina monopolar neuron L4
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lamina monopolar neuron L5
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lamina wide-field 1 neuron
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lamina wide-field 2 neuron
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lobula columnar neuron LC10
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lobula columnar neuron LC12
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lobula columnar neuron LC17
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medullary intrinsic neuron Mi1
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medullary intrinsic neuron Mi15
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medullary intrinsic neuron Mi4
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medullary intrinsic neuron Mi9
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neuron 1
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neuron 10
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neuron 11
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neuron 12
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neuron 13
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neuron 14
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neuron 15
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neuron 16
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neuron 17
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neuron 2
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neuron 3
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neuron 4
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neuron 5
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neuron 6
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neuron 7
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neuron 8
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neuron 9
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ocellus retinula cell
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octopaminergic/tyraminergic neuron
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olfactory receptor neuron
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optic-lobe-associated cortex glial cell
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outer photoreceptor cell
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pericerebral adult fat mass
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photoreceptor cell R7
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photoreceptor cell R8
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pigment cell
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Poxn neuron
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proximal medullary amacrine neuron Pm2
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proximal medullary amacrine neuron Pm4
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skeletal muscle of head
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subperineurial glial cell_head
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T neuron T2
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T neuron T2a
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T neuron T3
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T neuron T4/T5
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T neuron T4/T5a-b
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T neuron T4/T5c-d
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transmedullary neuron Tm1
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transmedullary neuron Tm2
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transmedullary neuron Tm20
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transmedullary neuron Tm29
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transmedullary neuron Tm3a
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transmedullary neuron Tm4
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transmedullary neuron Tm5c
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transmedullary neuron Tm9
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transmedullary Y neuron TmY14
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transmedullary Y neuron TmY4
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transmedullary Y neuron TmY5a
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transmedullary Y neuron TmY8
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unannotated
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View Datasets
Species-Related Single-Cell Datasets1Datasets
| DataID โ | Latin Name โ | Folder ID โ | Tissue โ | Title โ | Detail | QC | Analysis |
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| Data1192 | Drosophila melanogaster | GSE107451_Aging_Drosophila_Brain;Fly_Cell_Atlas_2022 | Whole body (18 tissues) | A single-cell transcriptome atlas of the aging Drosophila brain.;Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly | QC | Aging Analysis |
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