Connecting tubule cells

Connecting tubule (CNT) cells are specialized cells in the nephron that link the distal convoluted tubule to the collecting duct. They play a significant role in fine-tuning sodium, potassium, and acid-base balance. They are sensitive to aldosterone and reabsorb sodium while secreting potassium and protons. They express the calcium channel TRPV5 and are important for the final regulation of calcium reabsorption.