Skeletal myonuclei

Skeletal myonuclei are the multiple nuclei contained within a single, multinucleated skeletal muscle fiber (myofiber). They are post-mitotic and are responsible for gene expression to maintain the massive cytoplasmic volume of the myofiber. They are evenly distributed, but in some muscle types, they may be clustered near the neuromuscular junction or myotendinous junction.