Hallmarks of Aging Data Explorer

Explore twelve Hallmarks-of-Aging transcriptomic proxy programs across the full SP121 Human single-cell atlas. Scores are descriptive expression summaries, not direct functional assays or clinical biomarkers.

Interpretation boundary: higher scores indicate stronger expression of the selected proxy gene program. They do not uniformly mean more damage, faster aging, pathway activation, or causality. Age-association statistics remain unavailable until donor-level metadata and biological replicates are validated.
Summary CSVSignatures JSONManifest

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Group summary

Mean proxy score; bars are scaled within the selected hallmark.

SP121 cell-type reference UMAP

The same 12,000 sampled SP121 coordinates, colored by the validated cell-type labels used by content.php?SP_ID=SP121&analysis=longevity.

Open full SP121 atlas →
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Cell-type colors · same coordinates as the proxy UMAP above

The colored map displays the validated 12,000-point sample; legend counts are full 1,246,365-cell atlas totals. Context only: this view does not change the selected Hallmark score or establish age association, dysfunction, or causality.