AM-036-03-1A
De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.
Donor-Level Analysis Results
Matrix-backed CancerSCEM donor analysis for AM-036-03-1A, generated 2026-07-09 12:54:49 +0800.
1,999Cells analyzed
10Clusters
2,319Expressed genes
302.2Mean genes
Gene Program Summary
| Program | Clusters | Mean Score | Max Score | Genes Used |
|---|---|---|---|---|
| Proliferation | 10 | 0.263 | 0.5344 | 2 |
| Myeloid_APC | 10 | 0.0014 | 0.0096 | 4 |
| Epithelial_tumor | 10 | 0.0004 | 0.0035 | 1 |
| B_plasma | 10 | 0 | 0 | 0 |
| Endothelial | 10 | 0 | 0 | 0 |
| Checkpoint_exhaustion | 10 | 0 | 0 | 0 |
| Fibroblast_stroma | 10 | 0 | 0 | 0 |
| T_NK_cytotoxic | 10 | 0 | 0 | 1 |
Cluster QC
| Cluster | Cells | Mean UMI | Median Genes | Mean Mito % |
|---|---|---|---|---|
| cluster_5 | 282 | 198.5 | ||
| cluster_10 | 269 | 393 | ||
| cluster_6 | 259 | 351 | ||
| cluster_7 | 257 | 374 | ||
| cluster_2 | 249 | 353 | ||
| cluster_3 | 197 | 301 | ||
| cluster_4 | 196 | 304 | ||
| cluster_8 | 193 | 137 | ||
| cluster_9 | 74 | 173.5 | ||
| cluster_1 | 23 | 355 |
Top Cluster Marker Genes
| Cluster | Rank | Gene | Score | Mean Expr | Detect Fraction |
|---|---|---|---|---|---|
| cluster_9 | 1 | ISG15 | 1.9562 | 2.4525 | 0.9595 |
| cluster_7 | 1 | HSPA6 | 1.3041 | 1.6609 | 0.8016 |
| cluster_1 | 1 | JUN | 1.2686 | 3.8727 | 1 |
| cluster_2 | 1 | RASAL2 | 0.9871 | 1.9348 | 0.9558 |
| cluster_10 | 1 | S100A6 | 0.9767 | 2.9057 | 0.9963 |
| cluster_3 | 1 | HMCN1 | 0.8002 | 1.8755 | 0.9442 |
| cluster_6 | 1 | RPS8 | 0.7803 | 3.565 | 1 |
| cluster_4 | 1 | ISG15 | 0.7162 | 1.2147 | 0.7296 |
| cluster_5 | 1 | S100A4 | 0.2877 | 1.6443 | 0.8865 |
| cluster_8 | 1 | ADAMTSL4-AS1 | 0.1098 | 0.6926 | 0.5596 |
| cluster_7 | 2 | IER5 | 1.092 | 1.9698 | 0.9689 |
| cluster_9 | 2 | IFI6 | 1.0473 | 1.6567 | 0.9459 |
| cluster_1 | 2 | GIPC2 | 0.9803 | 1.1977 | 0.913 |
| cluster_10 | 2 | YBX1 | 0.9751 | 2.9119 | 1 |
| cluster_6 | 2 | BCAN | 0.7546 | 1.6693 | 0.9035 |
| cluster_2 | 2 | AKT3 | 0.7099 | 2.2779 | 0.992 |
| cluster_4 | 2 | RGS16 | 0.6784 | 1.1328 | 0.7704 |
| cluster_3 | 2 | LYST | 0.4922 | 1.6431 | 0.9239 |
| cluster_5 | 2 | ENO1 | 0.1829 | 1.4146 | 0.8723 |
| cluster_8 | 2 | ERRFI1 | 0.0751 | 0.2271 | 0.2746 |
| cluster_10 | 3 | S100A1 | 0.9594 | 2.4609 | 0.9926 |
| cluster_9 | 3 | GBP1 | 0.855 | 0.8701 | 0.6486 |
| cluster_7 | 3 | JUN | 0.8208 | 3.334 | 0.9961 |
| cluster_1 | 3 | IER5 | 0.8052 | 1.8142 | 0.9565 |
| cluster_6 | 3 | RPL5 | 0.7297 | 3.0973 | 1 |
| cluster_2 | 3 | NIBAN1 | 0.6597 | 1.604 | 0.8554 |
| cluster_4 | 3 | S100A4 | 0.5254 | 1.8711 | 0.9031 |
| cluster_3 | 3 | COL24A1 | 0.3859 | 0.8289 | 0.6751 |
| cluster_5 | 3 | HSPB7 | 0.0967 | 0.2057 | 0.2482 |
| cluster_8 | 3 | TENT5C | 0.0713 | 0.1721 | 0.2228 |
| cluster_10 | 4 | PRDX1 | 0.8193 | 1.8495 | 0.9851 |
| cluster_7 | 4 | AKT3 | 0.8052 | 2.3581 | 0.9961 |
| cluster_1 | 4 | SEMA4A | 0.7449 | 0.9846 | 0.7391 |
| cluster_6 | 4 | RPL11 | 0.7224 | 3.8624 | 1 |
| cluster_2 | 4 | ATP2B4 | 0.5561 | 1.3875 | 0.8675 |
| cluster_9 | 4 | GBP2 | 0.5184 | 0.5296 | 0.4865 |
| cluster_4 | 4 | RNF19B | 0.4964 | 0.9322 | 0.7653 |
| cluster_3 | 4 | AC099792.1 | 0.3679 | 0.689 | 0.6447 |
| cluster_5 | 4 | PBX1 | 0.0626 | 0.2299 | 0.2553 |
| cluster_8 | 4 | SEMA4A | 0.0608 | 0.3033 | 0.2694 |
Primary Metadata
Core de-identified metadata fields migrated from the ImmuneAging donor manifest.
Donor ID
AM-036-03-1A
Sample ID
AM-036-03-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Acral Melanoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Acral Melanoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
8,436
Analysis Status
Matrix available; UMAP generated by fallback sampled pipeline
UMAP Status
Ready
Metadata / Source Notes
Project ID: AM-036; Cancer type: Acral Melanoma; Source: NCBI (GEO); Accession: GSE215120; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: AM-036-03-1A.counts.matrix.tsv.gz (2.47 MB); Matrix integrity: gzip file ended before end-of-stream marker during UMAP generation; redownload required before UMAP can be generated.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv
Additional Clinical / Source Fields
Supplementary source metadata retained from the migrated manifest where available.
cancer type
Acral Melanoma
cancer type short
AM
library count
1
library sample ids
AM-036-03-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE215120; downloaded 2026-07-06
data accession
GSE215120
project id
AM-036
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE215120
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix incomplete; redownload required
matrix file name
AM-036-03-1A.counts.matrix.tsv.gz
matrix file size bytes
2588417
matrix file size mb
2.47
umap coordinates url
umap summary url
umap pipeline
Fallback Python normalize_total/log1p/HVG/SVD/UMAP; sampled 3000/8436 cells; generated 2026-07-09
matrix integrity status
Gzip EOF/truncated during UMAP generation