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ESCC-111-11-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

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Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-11-1A, generated 2026-07-09 12:54:49 +0800.

1,999Cells analyzed
20Clusters
22,318Expressed genes
9047Mean UMI
2420Mean genes
3.302Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 20 0.4495 2.6393 8
T_NK_cytotoxic 20 0.4131 1.726 10
Fibroblast_stroma 20 0.3497 2.7684 8
Myeloid_APC 20 0.3338 1.8648 9
Checkpoint_exhaustion 20 0.2296 0.9782 8
Proliferation 20 0.1821 1.7585 7
Endothelial 20 0.1196 1.1867 7
Epithelial_tumor 20 0.1023 1.5435 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 225 12051.7067 2787 3.6485
cluster_2 224 5128.0312 1960 3.3427
cluster_3 161 5089.9627 1837 3.7683
cluster_4 156 13933.6859 2515.5 0.6294
cluster_6 156 5919.0962 2304 2.6032
cluster_5 156 7495.6282 2584 3.2696
cluster_7 139 12812.3022 3721 4.2668
cluster_8 121 6958.2893 2481 5.4266
cluster_9 107 5494.0841 1871 4.3526
cluster_10 99 6461.0404 2237 3.0735
cluster_11 79 23411.8608 2295 1.1808
cluster_12 74 13046.4865 3727.5 4.1764
cluster_13 57 7103.8947 2071 3.9625
cluster_14 57 14899.9825 3330 3.1575
cluster_15 54 3597.4074 1566 3.0702
cluster_16 40 9997.025 3100.5 4.549
cluster_17 27 1160.5556 477 1.1357
cluster_18 26 12743.1923 4013.5 2.5806
cluster_19 25 6655.92 978 3.2112
cluster_20 16 6027.4375 2417.5 3.5247
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_4 1 KRT17 5.3026 5.3395 1
cluster_11 1 IGHG1 4.4396 4.4974 0.8481
cluster_7 1 COL1A1 4.3202 4.4983 0.9928
cluster_12 1 IGFBP7 4.1306 4.7331 1
cluster_14 1 CD74 3.6656 5.7734 1
cluster_1 1 IFI30 3.4709 3.8175 0.9956
cluster_16 1 TAGLN 3.3776 3.6604 0.975
cluster_19 1 FTL 3.1784 5.8484 1
cluster_20 1 CRYAB 3.0873 3.1975 0.9375
cluster_13 1 TPSAB1 3.0532 3.0546 0.9825
cluster_18 1 HIST1H4C 2.8929 3.4287 1
cluster_8 1 IGFBP7 2.6339 3.2299 0.9752
cluster_5 1 IL32 2.4447 3.4847 0.9872
cluster_9 1 CD74 2.4252 4.5077 0.9907
cluster_6 1 CCL5 2.3632 2.9692 0.9744
cluster_2 1 CCL5 2.2734 2.8091 0.9509
cluster_17 1 CXCL8 2.1786 2.7179 0.963
cluster_10 1 GNLY 2.1288 2.5759 0.7273
cluster_15 1 OASL 1.5012 1.7687 0.7778
cluster_3 1 IL7R 1.1503 1.6864 0.8075
cluster_4 2 S100A2 5.1351 5.1642 0.9808
cluster_11 2 IGKC 4.1572 4.2681 0.8354
cluster_7 2 COL1A2 3.9357 4.1238 1
cluster_12 2 SPARC 3.6029 4.0558 0.9865
cluster_14 2 HLA-DRA 3.4126 4.4826 0.9825
cluster_1 2 IL1B 3.1953 3.2835 0.8578
cluster_19 2 CCL18 3.1073 3.1704 0.8
cluster_13 2 TPSB2 2.8487 2.8505 0.9825
cluster_16 2 CALD1 2.8271 3.2926 1
cluster_18 2 STMN1 2.7456 3.1123 1
cluster_20 2 NRXN1 2.3745 2.3756 0.9375
cluster_9 2 HLA-DRA 2.3653 3.406 0.9907
cluster_5 2 TNFRSF4 2.2547 2.405 0.9551
cluster_6 2 GZMB 2.2129 2.6613 0.9679
cluster_8 2 COL4A1 1.9573 2.143 0.9091
cluster_2 2 NKG7 1.7938 2.2212 0.9107
cluster_10 2 AREG 1.7802 2.2006 0.9394
cluster_17 2 G0S2 1.5507 1.9499 0.8519
cluster_15 2 IFIT2 1.4104 1.5419 0.6296
cluster_3 2 CD3E 0.8694 1.5563 0.9068

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-11-1A
Sample ID
ESCC-111-11-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
2,367
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-11-1A.counts.matrix.tsv.gz (6.69 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=2367; raw genes=22432; Leiden clusters=20; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-11-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-11-1A.counts.matrix.tsv.gz
matrix file size bytes
7017634
matrix file size mb
6.69
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/ESCC-111-11-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-11-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-11-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=2367; raw_genes=22432; leiden_clusters=20; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated