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ESCC-111-13-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-13-1A, generated 2026-07-09 12:54:49 +0800.

1,998Cells analyzed
23Clusters
23,249Expressed genes
8107Mean UMI
2352Mean genes
3.629Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
Fibroblast_stroma 23 0.5528 2.7653 8
B_plasma 23 0.4417 1.9481 8
Myeloid_APC 23 0.3128 1.7759 9
Endothelial 23 0.2263 1.52 7
T_NK_cytotoxic 23 0.2258 1.4751 10
Epithelial_tumor 23 0.1982 1.5299 8
Proliferation 23 0.1783 1.5464 7
Checkpoint_exhaustion 23 0.1075 0.5079 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 259 5335.2239 1865 3.0162
cluster_2 239 6599.3556 2180 3.7166
cluster_3 183 6770.377 2530 5.1
cluster_4 176 12574.1989 3319.5 3.012
cluster_5 170 12258.5353 3379.5 3.0635
cluster_6 133 4057.6842 1567 2.9208
cluster_7 119 16760.5882 4056 5.7202
cluster_8 117 3728.1538 1444 3.5098
cluster_9 97 7339.4845 2459 3.6473
cluster_10 91 8562.6813 1905 2.6613
cluster_11 61 14028.7541 1785 2.3772
cluster_12 56 6375.9107 2416 5.6622
cluster_13 46 3516.1957 1263.5 3.5192
cluster_15 45 7007.5111 2364 5.4034
cluster_14 45 12755.8222 2809 3.3918
cluster_16 41 956.122 292 0.7273
cluster_17 39 4830.6667 1596 4.8059
cluster_18 17 10542 3231 4.7687
cluster_19 16 12619.4375 3638.5 3.7509
cluster_20 16 9044.4375 2972.5 4.2328
cluster_21 13 6944.4615 2552 3.5969
cluster_22 10 8123.4 2459.5 2.2794
cluster_23 9 5829 719 0.6249
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_23 1 S100A9 4.7631 5.0425 1
cluster_7 1 KRT14 4.61 4.6805 0.9916
cluster_18 1 PTGDS 3.9254 4.0888 0.8824
cluster_20 1 CCL21 3.9197 3.9317 0.875
cluster_10 1 CCL3L1 3.907 4.0708 0.956
cluster_14 1 CD74 3.7069 5.4809 1
cluster_4 1 DCN 3.6434 4.4908 1
cluster_22 1 GZMB 3.6321 3.8934 1
cluster_15 1 WFDC2 3.6031 3.6303 0.9778
cluster_5 1 COL1A1 3.4591 4.4259 1
cluster_11 1 IGKC 3.382 3.447 0.7213
cluster_8 1 GNLY 3.0032 3.1272 0.9316
cluster_13 1 TPSAB1 2.8989 2.9013 0.9783
cluster_21 1 CRYAB 2.8633 3.0315 1
cluster_12 1 ACKR1 2.7754 2.8299 1
cluster_19 1 HIST1H4C 2.751 3.099 0.9375
cluster_3 1 IGFBP7 2.4992 3.8325 1
cluster_17 1 CD74 2.4673 4.2766 1
cluster_16 1 CCL4L2 2.4507 2.8739 0.7317
cluster_9 1 RGS5 2.2398 2.3107 0.8247
cluster_2 1 COL1A1 2.2135 3.2098 0.9498
cluster_6 1 CCL5 1.955 2.2078 0.8722
cluster_1 1 CD7 1.7859 2.0985 0.9344
cluster_7 2 S100A2 4.5714 4.6672 1
cluster_23 2 S100A8 4.521 4.7359 1
cluster_10 2 CCL4L2 3.6899 3.9953 0.8901
cluster_4 2 MMP1 3.6033 4.1221 0.983
cluster_14 2 HLA-DRA 3.4632 4.2431 1
cluster_15 2 SLPI 3.273 3.3193 0.9111
cluster_22 2 GPR183 3.2547 3.5478 1
cluster_20 2 IGFBP7 3.0998 4.6372 1
cluster_11 2 JCHAIN 3.0838 3.1096 0.7049
cluster_5 2 COL1A2 3.0832 3.9878 1
cluster_18 2 CFD 2.9081 2.9927 1
cluster_13 2 TPSB2 2.6904 2.6932 0.9783
cluster_12 2 CCL14 2.5561 2.5872 0.9643
cluster_19 2 STMN1 2.4695 2.8668 1
cluster_3 2 PLVAP 2.3165 2.3858 0.9454
cluster_17 2 HLA-DRA 2.2495 3.0636 0.9744
cluster_21 2 CD74 2.2112 4.0543 1

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-13-1A
Sample ID
ESCC-111-13-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
4,049
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-13-1A.counts.matrix.tsv.gz (10.82 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=4049; raw genes=23946; Leiden clusters=23; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-13-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-13-1A.counts.matrix.tsv.gz
matrix file size bytes
11348927
matrix file size mb
10.82
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=4049; raw_genes=23946; leiden_clusters=23; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated