ESCC-111-14-1A
De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.
Donor-Level Analysis Results
Matrix-backed CancerSCEM donor analysis for ESCC-111-14-1A, generated 2026-07-09 12:54:49 +0800.
2,000Cells analyzed
10Clusters
1,006Expressed genes
101.7Mean genes
Gene Program Summary
| Program | Clusters | Mean Score | Max Score | Genes Used |
|---|---|---|---|---|
| Proliferation | 10 | 0.433 | 1.2401 | 1 |
| Myeloid_APC | 10 | 0.1781 | 1.7062 | 2 |
| Epithelial_tumor | 10 | 0.0634 | 0.468 | 1 |
| B_plasma | 10 | 0 | 0 | 0 |
| Endothelial | 10 | 0 | 0 | 0 |
| Checkpoint_exhaustion | 10 | 0 | 0 | 0 |
| Fibroblast_stroma | 10 | 0 | 0 | 0 |
| T_NK_cytotoxic | 10 | 0 | 0 | 0 |
Cluster QC
| Cluster | Cells | Mean UMI | Median Genes | Mean Mito % |
|---|---|---|---|---|
| cluster_10 | 329 | 153 | ||
| cluster_7 | 286 | 55.5 | ||
| cluster_3 | 268 | 86 | ||
| cluster_4 | 240 | 121 | ||
| cluster_5 | 212 | 121.5 | ||
| cluster_2 | 185 | 68 | ||
| cluster_6 | 174 | 80.5 | ||
| cluster_1 | 149 | 86 | ||
| cluster_8 | 90 | 137 | ||
| cluster_9 | 67 | 88 |
Top Cluster Marker Genes
| Cluster | Rank | Gene | Score | Mean Expr | Detect Fraction |
|---|---|---|---|---|---|
| cluster_8 | 1 | SFN | 2.3529 | 2.371 | 0.9778 |
| cluster_9 | 1 | C1QB | 1.7837 | 1.7927 | 0.6716 |
| cluster_3 | 1 | CD52 | 1.63 | 2.0085 | 0.9552 |
| cluster_10 | 1 | MFAP2 | 1.63 | 2.4759 | 0.9696 |
| cluster_4 | 1 | CCN1 | 1.2291 | 2.2539 | 0.8875 |
| cluster_5 | 1 | CCN1 | 1.1345 | 2.1866 | 0.8726 |
| cluster_7 | 1 | CD52 | 0.8461 | 1.3221 | 0.7587 |
| cluster_6 | 1 | HSPG2 | 0.4789 | 0.6552 | 0.454 |
| cluster_2 | 1 | JUN | 0.3427 | 2.4036 | 0.9297 |
| cluster_1 | 1 | NBL1 | 0.1971 | 1.0627 | 0.6577 |
| cluster_9 | 2 | C1QC | 1.7259 | 1.7322 | 0.6418 |
| cluster_8 | 2 | PRDX1 | 1.3454 | 2.4425 | 1 |
| cluster_10 | 2 | CCN1 | 1.2345 | 2.2038 | 0.8845 |
| cluster_4 | 2 | MFAP2 | 1.1849 | 2.1568 | 0.975 |
| cluster_5 | 2 | MFAP2 | 1.1178 | 2.1133 | 0.9481 |
| cluster_3 | 2 | TNFRSF18 | 0.9383 | 1.0022 | 0.694 |
| cluster_7 | 2 | LAPTM5 | 0.4746 | 0.8074 | 0.6748 |
| cluster_6 | 2 | ADGRL4 | 0.3795 | 0.3985 | 0.3563 |
| cluster_1 | 2 | MFAP2 | 0.1735 | 1.2746 | 0.6846 |
| cluster_2 | 2 | ID3 | 0.1703 | 1.5618 | 0.8486 |
| cluster_9 | 3 | C1QA | 1.6135 | 1.6197 | 0.6716 |
| cluster_10 | 3 | MXRA8 | 1.182 | 1.7881 | 0.9696 |
| cluster_8 | 3 | C1QTNF12 | 1.1241 | 1.13 | 0.7889 |
| cluster_4 | 3 | NBL1 | 1.0968 | 1.8455 | 0.9708 |
| cluster_5 | 3 | NBL1 | 0.9655 | 1.7435 | 0.9481 |
| cluster_3 | 3 | LAPTM5 | 0.8952 | 1.1759 | 0.8881 |
| cluster_6 | 3 | ID3 | 0.3771 | 1.7516 | 0.9023 |
| cluster_7 | 3 | LCK | 0.2206 | 0.3956 | 0.4336 |
| cluster_2 | 3 | CCN1 | 0.1404 | 1.2998 | 0.5892 |
| cluster_1 | 3 | WASF2 | 0.1098 | 0.4971 | 0.5906 |
| cluster_9 | 4 | LAPTM5 | 1.1874 | 1.5482 | 0.8657 |
| cluster_10 | 4 | CAPZB | 0.9972 | 2.0369 | 0.997 |
| cluster_8 | 4 | PGD | 0.9951 | 1.2335 | 0.8667 |
| cluster_5 | 4 | ID3 | 0.9559 | 2.2619 | 0.934 |
| cluster_4 | 4 | MXRA8 | 0.9027 | 1.5949 | 0.9583 |
| cluster_3 | 4 | LCK | 0.7158 | 0.8264 | 0.7687 |
| cluster_6 | 4 | TIE1 | 0.2456 | 0.2535 | 0.2586 |
| cluster_7 | 4 | PDE4B | 0.1756 | 0.3268 | 0.3427 |
| cluster_2 | 4 | GJA4 | 0.1242 | 0.1562 | 0.1243 |
| cluster_1 | 4 | MXRA8 | 0.1077 | 0.9003 | 0.604 |
Primary Metadata
Core de-identified metadata fields migrated from the ImmuneAging donor manifest.
Donor ID
ESCC-111-14-1A
Sample ID
ESCC-111-14-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
6,006
Analysis Status
Matrix available; UMAP generated by fallback sampled pipeline
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-14-1A.counts.matrix.tsv.gz (0.69 MB); Matrix integrity: gzip file ended before end-of-stream marker during UMAP generation; redownload required before UMAP can be generated.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv
Additional Clinical / Source Fields
Supplementary source metadata retained from the migrated manifest where available.
cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-14-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix incomplete; redownload required
matrix file name
ESCC-111-14-1A.counts.matrix.tsv.gz
matrix file size bytes
720642
matrix file size mb
0.69
umap coordinates url
umap summary url
umap pipeline
Fallback Python normalize_total/log1p/HVG/SVD/UMAP; sampled 3000/6006 cells; generated 2026-07-09
matrix integrity status
Gzip EOF/truncated during UMAP generation