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ESCC-111-21-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

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Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-21-1A, generated 2026-07-09 12:54:49 +0800.

1,999Cells analyzed
23Clusters
22,261Expressed genes
6302Mean UMI
1801Mean genes
3.411Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 23 0.7201 2.7041 8
T_NK_cytotoxic 23 0.4143 1.5617 10
Myeloid_APC 23 0.2287 1.1632 9
Checkpoint_exhaustion 23 0.1926 0.6429 8
Proliferation 23 0.1822 1.5796 7
Epithelial_tumor 23 0.1521 1.7901 8
Endothelial 23 0.0834 1.0919 7
Fibroblast_stroma 23 0.0689 1.4322 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 256 2830.7734 1184 3.2349
cluster_2 222 12868.5 3785 5.2403
cluster_3 208 5268.6346 1770 3.1956
cluster_4 166 2487.0301 1061 3.5965
cluster_5 150 3616.3067 1427.5 2.9183
cluster_6 142 5211.1197 1250 2.8757
cluster_7 124 2716.7097 1073.5 4.4958
cluster_8 116 17551.9569 1701 1.2007
cluster_9 100 3575.56 1448 3.4404
cluster_10 84 8818.4405 2135.5 2.9662
cluster_11 73 5136.2055 1968 5.528
cluster_12 55 4044.5455 1473 3.4109
cluster_13 49 4677.8163 1765 2.1711
cluster_14 49 3602.1429 1552 1.9839
cluster_15 47 4219.9149 1515 4.4275
cluster_16 46 9365.587 2203 2.9755
cluster_17 34 9491.4706 2214 4.298
cluster_18 20 21582.2 1670 1.1025
cluster_19 15 886.8 410 1.1765
cluster_20 14 10969.2857 3229.5 3.2344
cluster_21 13 9770.3846 1494 3.4257
cluster_22 12 1537.3333 622 0.7916
cluster_23 4 13539.25 1631 1.0712
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_23 1 IGLV1-44 8.5023 8.5544 1
cluster_18 1 IGHV3-74 8.034 8.1212 1
cluster_21 1 IGHV3-11 7.4106 7.5003 1
cluster_2 1 KRT14 3.9816 4.0985 0.9955
cluster_16 1 CD74 3.7832 5.6115 1
cluster_8 1 IGKC 3.3735 3.6372 0.8362
cluster_17 1 CD74 3.1911 5.0521 1
cluster_6 1 IL1B 3.122 3.1863 0.8873
cluster_11 1 IGFBP7 2.9116 3.2162 0.9863
cluster_9 1 TPSAB1 2.8157 2.8181 0.95
cluster_10 1 PERP 2.7977 3.3553 0.9524
cluster_13 1 CD74 2.6531 4.5033 1
cluster_14 1 GNLY 2.6162 3.1379 0.9184
cluster_20 1 TUBA1B 2.6009 3.3783 1
cluster_19 1 CXCL8 2.4867 2.8022 1
cluster_15 1 COL1A1 2.4037 2.4259 0.8085
cluster_7 1 CD74 2.1844 3.9642 1
cluster_12 1 GNLY 2.0053 2.536 0.7636
cluster_5 1 GNLY 1.9891 2.4257 0.74
cluster_3 1 IL32 1.9108 2.6947 0.9808
cluster_4 1 CCL5 1.7136 2.3011 0.9518
cluster_1 1 CD3E 0.7624 1.3657 0.9023
cluster_22 1 Z93241.1 0.7045 0.7442 0.6667
cluster_23 2 IGHV3-23 7.0401 7.1995 1
cluster_21 2 IGKC 5.5 5.9237 1
cluster_18 2 IGLV2-14 4.4702 4.7477 0.75
cluster_2 2 KRT17 3.8347 4.0204 0.991
cluster_16 2 HLA-DRA 3.7255 4.4851 1
cluster_8 2 IGHG1 3.2339 3.3915 0.8362
cluster_17 2 TXN 3.1066 3.9785 1
cluster_9 2 CPA3 2.6916 2.6964 0.95
cluster_10 2 IFI27 2.6207 3.3418 1
cluster_13 2 HLA-DRA 2.5493 3.3321 1
cluster_20 2 STMN1 2.5415 2.9701 1
cluster_6 2 G0S2 2.5136 2.6322 0.8451
cluster_15 2 SPARC 2.1351 2.2229 0.8723
cluster_7 2 HLA-DRA 2.0698 2.7868 0.9919
cluster_14 2 TRBV7-2 2.0057 2.0625 0.7347
cluster_11 2 SPARC 1.9956 2.0607 0.8904
cluster_19 2 G0S2 1.8359 2.1193 0.8

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-21-1A
Sample ID
ESCC-111-21-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
7,767
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-21-1A.counts.matrix.tsv.gz (16.95 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=7767; raw genes=24236; Leiden clusters=23; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-21-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-21-1A.counts.matrix.tsv.gz
matrix file size bytes
17773769
matrix file size mb
16.95
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/ESCC-111-21-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-21-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-21-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=7767; raw_genes=24236; leiden_clusters=23; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated