Home / Human Immune Atlas / Dataset Donors / ESCC-111-22-1A

ESCC-111-22-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Back to Dataset Donors Human Immune Atlas

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-22-1A, generated 2026-07-09 12:54:49 +0800.

1,999Cells analyzed
20Clusters
23,178Expressed genes
9530Mean UMI
2400Mean genes
3.569Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 20 0.3684 2.785 8
Fibroblast_stroma 20 0.3556 3.2564 8
Myeloid_APC 20 0.3246 2.0986 9
Epithelial_tumor 20 0.2634 1.3978 8
Endothelial 20 0.2559 1.7315 7
T_NK_cytotoxic 20 0.2475 1.4932 10
Proliferation 20 0.1868 0.4192 7
Checkpoint_exhaustion 20 0.1577 0.7691 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 241 6796.3029 2680 5.3975
cluster_2 200 12106.275 3556.5 4.4465
cluster_3 187 6237.0053 1409 2.7597
cluster_4 169 16011.497 3999 5.0277
cluster_5 157 6959.4459 2200 3.2917
cluster_6 155 6891.471 1596 2.011
cluster_7 130 12777.8154 2899 2.5844
cluster_8 128 6051.1953 1921.5 3.1347
cluster_9 115 24940.487 2501 1.7611
cluster_10 94 7529.7979 2887.5 5.2482
cluster_11 92 6355.2609 1454.5 3.6358
cluster_12 84 790.6905 287 0.9299
cluster_13 55 6786.1818 2322 2.5326
cluster_15 45 9617.9333 3072 4.6739
cluster_14 45 11432.9556 3210 3.4412
cluster_16 31 12446.8065 2816 3.9665
cluster_17 24 9576.4167 3062.5 3.8585
cluster_18 20 6003.65 2339 4.4536
cluster_19 17 9102.7647 882 2.0508
cluster_20 10 8399.5 2899 6.0995
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_2 1 COL1A1 4.7897 4.9899 0.99
cluster_17 1 TPSAB1 4.4023 4.4053 0.9583
cluster_19 1 S100A9 4.2435 4.7166 0.9412
cluster_9 1 IGKC 4.1992 4.2975 0.9304
cluster_16 1 CD74 4.1122 5.4413 1
cluster_4 1 KRT14 4.0485 4.7578 0.9882
cluster_7 1 IFI30 3.6015 4.1034 0.9846
cluster_11 1 IL1B 3.2902 3.567 0.9783
cluster_13 1 GNLY 3.195 3.327 0.8
cluster_15 1 SPARC 3.0188 4.0554 0.9778
cluster_14 1 IL32 3.0035 3.8525 1
cluster_8 1 CCL5 2.9517 3.0984 0.9688
cluster_6 1 KRT14 2.884 3.712 0.9935
cluster_10 1 IGFBP7 2.8362 4.1334 1
cluster_18 1 CRYAB 2.7237 2.8891 1
cluster_1 1 IGFBP7 2.6557 3.7661 0.9959
cluster_20 1 SEMA3A 2.5313 2.5784 1
cluster_3 1 S100A2 2.1843 2.9019 0.9412
cluster_12 1 CXCL8 2.182 2.7497 0.9881
cluster_5 1 CD3E 1.6842 1.8839 0.8981
cluster_2 2 COL1A2 4.2711 4.3929 0.995
cluster_9 2 IGHG1 4.1934 4.2571 0.9391
cluster_19 2 KRT17 4.1475 4.7746 1
cluster_17 2 CPA3 3.8365 3.8381 0.9583
cluster_16 2 HLA-DRA 3.708 4.2845 1
cluster_7 2 CD74 3.5841 4.7438 1
cluster_4 2 KRT6A 3.2602 3.7886 0.9645
cluster_15 2 IGFBP7 2.9755 4.339 0.9778
cluster_14 2 CD7 2.8377 3.1689 1
cluster_10 2 PLVAP 2.7112 3.0304 1
cluster_11 2 PLAUR 2.5634 3.133 1
cluster_18 2 IGFBP5 2.5259 2.7315 1
cluster_20 2 CCL21 2.4835 2.4866 1
cluster_8 2 NKG7 2.3768 2.514 0.9141
cluster_6 2 KRT6A 2.2809 2.908 0.9806
cluster_13 2 CCL5 2.2389 2.513 0.7818
cluster_1 2 PLVAP 2.219 2.3982 0.9668
cluster_12 2 G0S2 2.1752 2.6281 0.9762
cluster_3 2 KRT14 1.7427 2.6313 0.8717
cluster_5 2 IL32 1.6662 2.452 0.9427

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-22-1A
Sample ID
ESCC-111-22-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
3,953
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-22-1A.counts.matrix.tsv.gz (11.07 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=3953; raw genes=24093; Leiden clusters=20; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-22-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-22-1A.counts.matrix.tsv.gz
matrix file size bytes
11608524
matrix file size mb
11.07
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/ESCC-111-22-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-22-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-22-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=3953; raw_genes=24093; leiden_clusters=20; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated