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ESCC-111-23-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

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Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-23-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
21Clusters
22,698Expressed genes
6524Mean UMI
2049Mean genes
2.656Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 21 0.4932 2.3639 8
T_NK_cytotoxic 21 0.4063 1.8676 10
Myeloid_APC 21 0.4004 1.8098 9
Epithelial_tumor 21 0.2578 1.6242 8
Checkpoint_exhaustion 21 0.247 1.3315 8
Proliferation 21 0.1814 1.9735 7
Fibroblast_stroma 21 0.1081 1.7858 8
Endothelial 21 0.1022 1.3507 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 280 5619.5857 2199.5 2.2148
cluster_2 240 6151.7625 2425 2.6178
cluster_3 239 3996.2385 1686 3.1536
cluster_4 206 7287.1262 1522 0.804
cluster_5 178 5095.3708 1843.5 2.9058
cluster_6 159 5755.1887 2106 3.2937
cluster_7 98 6525.3673 2625.5 5.0675
cluster_8 91 12391.6703 2805 3.1014
cluster_9 68 3078.0735 704 1.744
cluster_10 67 1028.9403 387 1.1106
cluster_11 63 11707.7143 3449 4.1038
cluster_12 61 7185.1311 2376 4.3969
cluster_13 57 5139.2632 1760 3.7801
cluster_14 39 22437.641 2052 0.674
cluster_15 30 13608.6 4092 2.1162
cluster_16 28 7387.6071 1002.5 1.2713
cluster_17 26 12985.6923 3127 2.0149
cluster_18 25 3585 1150 4.2104
cluster_19 21 852.7143 547 1.0566
cluster_20 15 11443.5333 2871 3.0913
cluster_21 9 11047.5556 2819 4.1233
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_16 1 S100A9 4.7863 5.2962 1
cluster_14 1 IGHG1 4.5025 4.5503 0.9231
cluster_21 1 KRT14 3.6023 3.8181 1
cluster_8 1 IFI30 3.4045 3.7232 0.9451
cluster_20 1 CCL22 3.3637 3.3684 1
cluster_17 1 CD74 3.3589 5.5186 1
cluster_6 1 GNLY 3.1961 3.8892 0.956
cluster_7 1 IGFBP7 3.1926 3.3136 0.9796
cluster_4 1 KRT17 3.1424 3.5395 0.966
cluster_15 1 STMN1 3.1353 3.3897 1
cluster_18 1 TPSAB1 2.9282 2.9317 0.92
cluster_11 1 KRT17 2.7844 3.4175 0.9206
cluster_9 1 FTL 2.5043 4.7182 1
cluster_12 1 DCN 2.4516 2.4678 0.9344
cluster_13 1 HLA-DRA 2.3728 3.2906 1
cluster_5 1 CCL5 2.2011 3.0048 0.9551
cluster_1 1 CCL5 2.1924 2.8851 0.9714
cluster_10 1 CXCL8 2.0855 2.3893 0.8955
cluster_2 1 IL32 2.0503 3.2388 0.9625
cluster_19 1 CROCC 0.7661 0.827 0.7619
cluster_3 1 IL7R 0.6704 1.0753 0.5732
cluster_16 2 S100A8 4.2923 4.558 1
cluster_14 2 IGKC 3.6798 3.7607 0.7436
cluster_20 2 FSCN1 3.1532 3.2989 0.9333
cluster_17 2 HLA-DRA 3.1209 4.0658 1
cluster_21 2 S100A2 3.0915 3.6397 1
cluster_15 2 TUBA1B 3.0234 3.8665 1
cluster_8 2 IL1B 3.0088 3.1027 0.8791
cluster_4 2 KRT6A 2.8996 3.1722 0.966
cluster_11 2 S100A2 2.769 3.244 0.8889
cluster_18 2 CPA3 2.6263 2.6306 0.96
cluster_12 2 COL1A2 2.4339 2.4557 0.918
cluster_13 2 CD74 2.3152 4.4526 0.9825
cluster_7 2 SPARCL1 2.2995 2.3544 0.9082
cluster_9 2 C1QC 2.208 2.3127 0.9118
cluster_5 2 GNLY 2.0996 2.86 0.8202
cluster_6 2 AREG 1.8663 2.172 0.9182
cluster_1 2 NKG7 1.792 2.4494 0.9286
cluster_2 2 FOXP3 1.7429 1.8478 0.9
cluster_10 2 G0S2 1.6873 1.9598 0.8657

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-23-1A
Sample ID
ESCC-111-23-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
4,492
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-23-1A.counts.matrix.tsv.gz (10.81 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=4492; raw genes=23741; Leiden clusters=21; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-23-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-23-1A.counts.matrix.tsv.gz
matrix file size bytes
11335470
matrix file size mb
10.81
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/ESCC-111-23-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-23-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-23-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=4492; raw_genes=23741; leiden_clusters=21; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated