Home / Human Immune Atlas / Dataset Donors / ESCC-111-25-1A

ESCC-111-25-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Back to Dataset Donors Human Immune Atlas

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-25-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
21Clusters
21,387Expressed genes
6434Mean UMI
2138Mean genes
1.916Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
T_NK_cytotoxic 21 0.8269 2.3307 10
Checkpoint_exhaustion 21 0.3949 1.1629 8
B_plasma 21 0.2833 1.6463 8
Proliferation 21 0.2439 1.5685 7
Myeloid_APC 21 0.1864 1.2262 9
Epithelial_tumor 21 0.1278 0.9594 8
Endothelial 21 0.1051 0.7724 7
Fibroblast_stroma 21 0.0925 1.8148 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 302 6083.4205 2202 2.0214
cluster_2 275 9219.4436 2105 0.44
cluster_3 241 4728.9751 2039 1.5124
cluster_4 164 7006.5732 2498.5 2.1052
cluster_5 148 4476.3581 1689.5 2.3787
cluster_6 141 6373.8865 1712 2.8013
cluster_7 129 9151.186 1956 0.268
cluster_8 93 6273.1935 2318 2.0529
cluster_9 82 10639.2805 3436.5 1.9229
cluster_10 74 5631.0676 2171 1.3813
cluster_11 72 7287.2361 2552.5 1.9237
cluster_12 58 2674.4655 1049.5 3.0862
cluster_13 54 5515.1667 2154.5 3.162
cluster_14 48 1954.8125 1056.5 4.2237
cluster_15 45 2565.2667 1402 4.6789
cluster_16 15 13207.1333 1780 2.5374
cluster_17 14 5003.7143 1813.5 1.8235
cluster_18 14 3348.8571 1506.5 6.5143
cluster_19 14 844.3571 302.5 0.4105
cluster_20 13 5164 2401 5.0567
cluster_21 4 2882.75 1093.5 7.569
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_17 1 TPSAB1 3.9134 3.9138 1
cluster_2 1 S100A2 3.8464 4.189 0.9964
cluster_20 1 CCL21 3.7706 3.7757 1
cluster_7 1 S100A2 3.5814 4.2219 0.9767
cluster_18 1 COL1A1 3.3579 3.3661 0.8571
cluster_19 1 CXCL8 2.7646 2.8512 0.9286
cluster_6 1 IFI30 2.3599 2.5282 0.9291
cluster_11 1 TRBV5-4 2.2429 2.3122 0.9444
cluster_9 1 STMN1 2.2117 2.8451 0.9756
cluster_4 1 TNFRSF4 2.205 2.2738 0.8841
cluster_15 1 IGFBP7 2.1937 2.3136 0.9778
cluster_10 1 TRAV12-3 2.1894 2.3187 0.9595
cluster_3 1 GNLY 2.1671 3.8029 0.9419
cluster_1 1 DNAJB1 2.1591 4.083 0.9834
cluster_16 1 IGHG1 2.0806 2.0847 0.4667
cluster_13 1 GZMA 1.9972 3.2553 0.8889
cluster_21 1 CLDN4 1.843 1.8676 0.75
cluster_8 1 DNAJB1 1.7079 3.8784 0.9892
cluster_5 1 HSPA1A 0.9533 3.6757 0.9527
cluster_12 1 MALAT1 0.7144 4.0627 1
cluster_14 1 PPP1R16B 0.6037 0.9616 0.7292
cluster_17 2 TPSB2 3.4467 3.4467 1
cluster_2 2 FABP5 3.4223 4.3701 0.9891
cluster_7 2 KRT17 3.0836 3.6193 0.9767
cluster_18 2 COL1A2 2.8167 2.8248 1
cluster_20 2 IGFBP7 2.3629 2.5168 0.9231
cluster_19 2 G0S2 2.3517 2.4401 1
cluster_6 2 TYROBP 2.3485 2.4571 0.9007
cluster_11 2 GNLY 2.1657 3.9846 0.9722
cluster_9 2 HMGB2 2.1646 2.8073 1
cluster_10 2 TRBV24-1 2.1121 2.2407 0.9324
cluster_16 2 JCHAIN 2.0574 2.0637 0.5333
cluster_3 2 CCL5 1.9502 3.4893 0.9959
cluster_4 2 S100A4 1.9116 3.1132 0.939
cluster_1 2 NKG7 1.8965 3.1713 1
cluster_21 2 ELF3 1.7845 1.8181 1
cluster_13 2 GNLY 1.7512 3.6009 0.9259
cluster_15 2 HSPG2 1.6434 1.6632 0.8889
cluster_8 2 HSPA1B 1.5668 3.7593 1
cluster_5 2 DNAJB1 0.8181 3.0075 0.8986

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-25-1A
Sample ID
ESCC-111-25-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
3,678
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-25-1A.counts.matrix.tsv.gz (8.93 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=3678; raw genes=21812; Leiden clusters=21; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-25-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-25-1A.counts.matrix.tsv.gz
matrix file size bytes
9360516
matrix file size mb
8.93
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/ESCC-111-25-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-25-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-25-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=3678; raw_genes=21812; leiden_clusters=21; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated