ESCC-111-26-1A
De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.
Donor-Level Analysis Results
Matrix-backed CancerSCEM donor analysis for ESCC-111-26-1A, generated 2026-07-09 12:54:49 +0800.
1,999Cells analyzed
10Clusters
5,931Expressed genes
528.4Mean genes
Gene Program Summary
| Program | Clusters | Mean Score | Max Score | Genes Used |
|---|---|---|---|---|
| Epithelial_tumor | 10 | 0.4535 | 1.5072 | 3 |
| B_plasma | 10 | 0.3867 | 3.3549 | 2 |
| T_NK_cytotoxic | 10 | 0.2893 | 1.7597 | 2 |
| Proliferation | 10 | 0.2133 | 0.74 | 2 |
| Checkpoint_exhaustion | 10 | 0.1473 | 0.6606 | 3 |
| Myeloid_APC | 10 | 0.1358 | 0.4248 | 5 |
| Endothelial | 10 | 0.0134 | 0.0494 | 1 |
| Fibroblast_stroma | 10 | 0.0091 | 0.0699 | 2 |
Cluster QC
| Cluster | Cells | Mean UMI | Median Genes | Mean Mito % |
|---|---|---|---|---|
| cluster_9 | 347 | 284 | ||
| cluster_4 | 267 | 504 | ||
| cluster_6 | 245 | 660 | ||
| cluster_7 | 243 | 436 | ||
| cluster_3 | 208 | 439 | ||
| cluster_1 | 199 | 928 | ||
| cluster_8 | 178 | 366 | ||
| cluster_2 | 164 | 703 | ||
| cluster_5 | 103 | 395 | ||
| cluster_10 | 45 | 504 |
Top Cluster Marker Genes
| Cluster | Rank | Gene | Score | Mean Expr | Detect Fraction |
|---|---|---|---|---|---|
| cluster_10 | 1 | IGKC | 3.7887 | 3.8386 | 0.7556 |
| cluster_6 | 1 | YBX1 | 2.5739 | 4.4259 | 1 |
| cluster_1 | 1 | TACSTD2 | 2.511 | 3.1017 | 0.9749 |
| cluster_7 | 1 | GNLY | 2.2106 | 2.3007 | 0.7901 |
| cluster_5 | 1 | LAPTM5 | 1.6212 | 2.0507 | 0.9806 |
| cluster_4 | 1 | CSTA | 1.5362 | 2.1506 | 0.9176 |
| cluster_2 | 1 | GSTM1 | 1.3187 | 2.2925 | 0.8598 |
| cluster_8 | 1 | CXCR4 | 1.1207 | 1.6128 | 0.8146 |
| cluster_9 | 1 | IL1B | 1.0334 | 1.064 | 0.3285 |
| cluster_3 | 1 | S100A4 | 1.017 | 1.4938 | 0.7596 |
| cluster_10 | 2 | JCHAIN | 2.848 | 2.8712 | 0.6889 |
| cluster_6 | 2 | GSTM3 | 2.4588 | 3.2091 | 0.9673 |
| cluster_1 | 2 | ATF3 | 2.4203 | 3.0402 | 0.9899 |
| cluster_4 | 2 | S100A11 | 1.439 | 3.1679 | 1 |
| cluster_7 | 2 | CD8A | 1.415 | 1.5096 | 0.8395 |
| cluster_5 | 2 | CD55 | 1.286 | 1.5448 | 0.9417 |
| cluster_2 | 2 | GSTM3 | 1.2771 | 2.224 | 0.8902 |
| cluster_8 | 2 | DUSP2 | 1.1133 | 1.6485 | 0.8708 |
| cluster_9 | 2 | G0S2 | 0.992 | 1.0156 | 0.3545 |
| cluster_3 | 2 | TNFRSF4 | 0.8334 | 0.8582 | 0.524 |
| cluster_1 | 3 | ELF3 | 2.3659 | 2.9408 | 0.9799 |
| cluster_6 | 3 | GSTM1 | 2.3032 | 3.1029 | 0.9796 |
| cluster_10 | 3 | IGKV3-20 | 2.2116 | 2.2294 | 0.4667 |
| cluster_7 | 3 | CXCL13 | 1.3708 | 1.4193 | 0.7366 |
| cluster_2 | 3 | MIR205HG | 1.262 | 1.7551 | 0.878 |
| cluster_5 | 3 | CXCR4 | 1.2297 | 1.7583 | 0.932 |
| cluster_4 | 3 | S100A2 | 1.1629 | 2.0653 | 0.8914 |
| cluster_9 | 3 | CXCL8 | 0.9717 | 1.2938 | 0.4438 |
| cluster_8 | 3 | PTPRC | 0.7742 | 1.2909 | 0.8596 |
| cluster_3 | 3 | ICOS | 0.72 | 0.8564 | 0.5817 |
| cluster_6 | 4 | PRDX1 | 2.2328 | 3.7276 | 1 |
| cluster_1 | 4 | SFN | 1.9389 | 2.5267 | 0.9497 |
| cluster_10 | 4 | ITM2C | 1.8815 | 2.0846 | 0.9111 |
| cluster_7 | 4 | CD52 | 1.3309 | 1.658 | 0.9424 |
| cluster_2 | 4 | SFN | 1.2198 | 1.9005 | 0.8415 |
| cluster_5 | 4 | LY9 | 1.1751 | 1.2107 | 0.7864 |
| cluster_4 | 4 | YBX1 | 1.1024 | 3.1226 | 0.9925 |
| cluster_9 | 4 | CXCL2 | 0.863 | 0.8851 | 0.3429 |
| cluster_3 | 4 | PTPRC | 0.6881 | 1.2021 | 0.7452 |
| cluster_8 | 4 | ZFP36L2 | 0.651 | 1.6693 | 0.8708 |
Primary Metadata
Core de-identified metadata fields migrated from the ImmuneAging donor manifest.
Donor ID
ESCC-111-26-1A
Sample ID
ESCC-111-26-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
5,911
Analysis Status
Matrix available; UMAP generated by fallback sampled pipeline
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-26-1A.counts.matrix.tsv.gz (3.69 MB); Matrix integrity: gzip file ended before end-of-stream marker during UMAP generation; redownload required before UMAP can be generated.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv
Additional Clinical / Source Fields
Supplementary source metadata retained from the migrated manifest where available.
cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-26-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix incomplete; redownload required
matrix file name
ESCC-111-26-1A.counts.matrix.tsv.gz
matrix file size bytes
3866370
matrix file size mb
3.69
umap coordinates url
umap summary url
umap pipeline
Fallback Python normalize_total/log1p/HVG/SVD/UMAP; sampled 3000/5911 cells; generated 2026-07-09
matrix integrity status
Gzip EOF/truncated during UMAP generation