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ESCC-111-33-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

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Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for ESCC-111-33-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
24Clusters
24,060Expressed genes
7160Mean UMI
2155Mean genes
3.465Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 24 0.5228 2.3635 8
Myeloid_APC 24 0.4265 2.2339 9
T_NK_cytotoxic 24 0.3636 2.0352 10
Epithelial_tumor 24 0.2748 1.7399 8
Endothelial 24 0.2081 1.6325 7
Checkpoint_exhaustion 24 0.1984 0.8247 8
Proliferation 24 0.1773 0.5764 7
Fibroblast_stroma 24 0.1734 2.3861 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 249 4417.9357 1697 3.5316
cluster_2 183 6233.9126 2234 2.2109
cluster_3 163 5627.7791 2079 3.2315
cluster_4 159 7586.0629 2663 5.7558
cluster_5 157 6166.0064 2199 3.5242
cluster_6 153 4968.366 1809 3.6238
cluster_7 128 5746.1016 1457 2.9185
cluster_8 114 9396.5789 2245 3.5604
cluster_9 85 5838.8706 2247 2.5423
cluster_10 71 22368.4507 2085 1.3212
cluster_11 70 3796.6857 1340.5 4.0594
cluster_12 65 5314.9385 1678 3.2739
cluster_13 64 4606.3438 1591.5 5.3084
cluster_14 56 13670.25 3267 2.8069
cluster_15 53 12774.2264 2867 3.1723
cluster_16 42 6791.4048 2345 3.813
cluster_17 40 8433.35 2539 6.1005
cluster_18 31 8873.3871 2926 2.6499
cluster_19 28 18587.3571 3356 3.9248
cluster_20 23 7080.5217 2490 5.1022
cluster_21 21 1625.7619 393 0.7345
cluster_22 20 7165.85 2709.5 2.4723
cluster_23 18 10351.7778 2884 2.1395
cluster_24 7 6135.4286 2387 3.9254
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_15 1 KRT14 4.0633 4.6294 1
cluster_16 1 TPSAB1 4.0522 4.0548 1
cluster_19 1 HLA-DRA 4.0245 5.0779 1
cluster_24 1 CCL21 3.8523 3.8541 0.8571
cluster_17 1 COL1A1 3.7234 3.7884 0.975
cluster_4 1 IGFBP7 3.638 3.9218 0.9874
cluster_10 1 IGHG1 3.6327 3.6654 0.8028
cluster_23 1 GZMB 3.6021 4.3201 0.9444
cluster_14 1 IFI30 3.5132 4.0362 1
cluster_20 1 IGFBP7 3.5042 4.0369 0.9565
cluster_12 1 S100A9 3.4829 4.0892 0.9846
cluster_5 1 KRT14 3.3123 3.726 0.9809
cluster_7 1 IL1B 3.2082 3.3779 0.9609
cluster_8 1 KRT19 3.0534 3.1089 0.9561
cluster_22 1 IFI27 3.0388 3.7365 1
cluster_6 1 GNLY 2.5887 3.1339 0.8824
cluster_18 1 BACH2 2.3807 2.5612 1
cluster_9 1 GNLY 2.3184 2.9632 0.9882
cluster_21 1 S100A8 2.2984 2.8703 0.9048
cluster_2 1 CCL5 2.2822 3.2887 0.9836
cluster_13 1 HLA-DRA 2.0414 3.0858 1
cluster_3 1 IL32 1.7779 2.9648 0.9448
cluster_1 1 CXCR4 1.0764 1.6902 0.8795
cluster_11 1 CXCL13 0.8816 1.2573 0.4286
cluster_19 2 CD74 3.817 6.1929 1
cluster_17 2 COL1A2 3.5336 3.5689 1
cluster_16 2 TPSB2 3.4889 3.4913 1
cluster_14 2 C1QC 3.4471 3.4775 0.9464
cluster_15 2 S100A2 3.4365 3.9312 0.9811
cluster_12 2 KRT14 3.4107 3.9736 1
cluster_24 2 IGFBP7 3.2298 3.7915 1
cluster_10 2 MZB1 3.1483 3.2038 1
cluster_23 2 GPR183 3.0655 3.4426 1
cluster_7 2 CCL3 2.9083 3.2622 0.9297
cluster_20 2 SPARC 2.8802 3.1678 0.9565
cluster_22 2 IGFBP7 2.7851 3.3302 1
cluster_5 2 S100A2 2.6929 3.0673 0.9618
cluster_8 2 KRT6A 2.552 2.9644 0.9912
cluster_4 2 IFI27 2.3509 2.892 0.956
cluster_18 2 CD79A 2.3362 2.4842 1

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
ESCC-111-33-1A
Sample ID
ESCC-111-33-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Esophageal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Esophageal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
4,201
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: ESCC-111; Cancer type: Esophageal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE160269; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: ESCC-111-33-1A.counts.matrix.tsv.gz (10.85 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=4201; raw genes=25377; Leiden clusters=24; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Esophageal Squamous Cell Carcinoma
cancer type short
ESCC
library count
1
library sample ids
ESCC-111-33-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE160269; downloaded 2026-07-06
data accession
GSE160269
project id
ESCC-111
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE160269
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
ESCC-111-33-1A.counts.matrix.tsv.gz
matrix file size bytes
11379722
matrix file size mb
10.85
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/ESCC-111-33-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-33-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/ESCC-111-33-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=4201; raw_genes=25377; leiden_clusters=24; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated