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GBC-066-02-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for GBC-066-02-1A, generated 2026-07-09 12:54:49 +0800.

1,999Cells analyzed
18Clusters
20,620Expressed genes
5811Mean UMI
1730Mean genes
2.603Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 18 0.693 2.0107 8
Myeloid_APC 18 0.4818 1.7415 9
T_NK_cytotoxic 18 0.335 1.3801 10
Proliferation 18 0.1897 1.7055 7
Checkpoint_exhaustion 18 0.1611 0.5456 8
Fibroblast_stroma 18 0.1586 2.6395 8
Epithelial_tumor 18 0.061 0.681 8
Endothelial 18 0.0355 0.1942 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 391 4595.0537 1445 3.2335
cluster_2 283 3349.4417 1258 2.8344
cluster_3 238 3565.4034 1335.5 2.8333
cluster_4 189 5074.3862 1714 2.6034
cluster_5 144 3706.2569 925 2.0654
cluster_6 118 4481.9661 1652.5 2.5271
cluster_7 90 3850.5111 1483.5 2.9392
cluster_8 85 14262.1176 2807 2.292
cluster_9 82 6894.4634 2198.5 1.913
cluster_10 66 9887.8333 1762 2.2738
cluster_11 65 13403.1231 3273 1.5709
cluster_12 59 4136.8136 1701 2.6407
cluster_13 59 18014.0339 1647 0.9203
cluster_14 47 7134.3404 2403 1.9548
cluster_15 28 3422.1786 1173.5 2.5803
cluster_16 25 11609.28 2493 2.3725
cluster_17 21 13642.7619 3523 2.4887
cluster_18 9 4272.8889 1678 2.4069
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_17 1 TAGLN 3.8553 3.8758 0.9524
cluster_8 1 LYZ 3.6627 3.8472 0.9647
cluster_16 1 TXN 3.5137 4.1254 1
cluster_18 1 TPSB2 3.5094 3.5094 1
cluster_10 1 APOC1 3.4532 3.5218 0.9848
cluster_15 1 S100A8 3.4423 3.5881 1
cluster_14 1 GZMB 3.1936 3.3395 1
cluster_11 1 STMN1 2.981 3.3058 1
cluster_13 1 JCHAIN 2.7225 2.9072 0.7966
cluster_12 1 CCL5 2.4607 2.9086 0.9492
cluster_9 1 MS4A1 2.3714 2.809 0.9878
cluster_1 1 HLA-DRA 2.1667 3.5129 0.9974
cluster_5 1 LCN2 2.1487 2.1929 0.8611
cluster_6 1 IL32 1.9957 2.8282 0.9915
cluster_7 1 GNLY 1.8513 1.9344 0.6778
cluster_2 1 CCL5 1.7658 2.0363 0.9187
cluster_4 1 CD3E 1.1275 1.8977 0.9788
cluster_3 1 SARAF 0.838 2.3844 0.9958
cluster_17 2 TIMP1 3.852 4.3175 1
cluster_8 2 HLA-DRA 3.5906 5.208 1
cluster_18 2 TPSAB1 3.4548 3.4552 1
cluster_10 2 FTL 3.4362 5.6621 1
cluster_15 2 S100A9 3.3385 3.5652 1
cluster_11 2 TUBA1B 2.9297 4.0347 1
cluster_16 2 HLA-DRA 2.8313 4.5659 1
cluster_13 2 SSR4 2.6524 3.4932 1
cluster_14 2 PTGDS 2.3586 2.4125 0.6809
cluster_9 2 HLA-DRA 2.2549 3.9325 1
cluster_12 2 GZMB 2.0784 2.238 0.9831
cluster_5 2 S100A9 1.9747 2.1059 0.7986
cluster_1 2 CD74 1.9129 4.5593 1
cluster_7 2 XCL1 1.6445 1.6973 0.7778
cluster_6 2 TNFRSF4 1.4934 1.6419 0.8983
cluster_2 2 CST7 1.3607 1.7241 0.894
cluster_4 2 IL32 1.0399 1.8919 0.9365
cluster_3 2 CD3E 0.8373 1.6145 0.979
cluster_17 3 SPARC 3.8238 3.8419 0.9524
cluster_8 3 CST3 3.5451 4.0092 1
cluster_18 3 CPA3 3.139 3.1394 1
cluster_11 3 TUBB 2.9232 3.5882 1

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
GBC-066-02-1A
Sample ID
GBC-066-02-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Gallbladder Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Gallbladder Carcinoma; Normal
Tissue / Cell Source
Normal
Modality
scRNA-seq (10X Genomics)
Cell Count
2,527
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: GBC-066; Cancer type: Gallbladder Carcinoma; Source: NCBI (GEO); Accession: GSE201425; Country: CHN; Sample type: Normal; Protocol: 10X Genomics; Matrix: GBC-066-02-1A.counts.matrix.tsv.gz (5.27 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=2527; raw genes=21121; Leiden clusters=18; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Gallbladder Carcinoma
cancer type short
GBC
library count
1
library sample ids
GBC-066-02-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE201425; downloaded 2026-07-06
data accession
GSE201425
project id
GBC-066
sample type
Normal
country
CHN
data source
NCBI (GEO)
accession no
GSE201425
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
GBC-066-02-1A.counts.matrix.tsv.gz
matrix file size bytes
5531227
matrix file size mb
5.27
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=2527; raw_genes=21121; leiden_clusters=18; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated