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HCC-090-05-1H

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for HCC-090-05-1H, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
19Clusters
20,435Expressed genes
4343Mean UMI
1394Mean genes
6.833Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 19 0.9193 2.4165 8
Myeloid_APC 19 0.7841 2.5248 9
Endothelial 19 0.1307 0.643 7
Proliferation 19 0.1288 0.9264 7
Epithelial_tumor 19 0.099 1.5265 6
T_NK_cytotoxic 19 0.0903 0.5933 10
Checkpoint_exhaustion 19 0.0527 0.1605 8
Fibroblast_stroma 19 0.0093 0.102 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 299 2378.9264 1098 6.6651
cluster_2 282 4049.4326 1393 7.2784
cluster_3 239 4962.8996 928 6.938
cluster_4 220 5131.5773 1563.5 7.7193
cluster_5 162 3740.2469 1421.5 6.7012
cluster_6 144 8186.9444 2298 7.1611
cluster_7 114 2489.7105 923 6.9
cluster_8 95 5836.6105 1692 6.9012
cluster_9 79 9357.8481 2109 7.2152
cluster_10 73 3100.3836 1069 7.6947
cluster_11 64 3083.3281 1273 5.8223
cluster_12 59 2195.7797 777 4.2497
cluster_13 48 4812.0417 740 4.3183
cluster_14 36 2784.0278 1332.5 7.4807
cluster_15 25 2273.4 1049 5.1971
cluster_16 20 3812.2 1166.5 7.14
cluster_17 19 2866.8947 1315 5.3923
cluster_18 14 4733.1429 405 3.7147
cluster_19 8 2153.5 816.5 5.8719
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_18 1 HBB 7.0171 7.262 1
cluster_13 1 IGHG3 6.1248 6.4901 1
cluster_19 1 TPSB2 5.2179 5.2272 1
cluster_6 1 C1QB 3.9625 4.3586 0.9931
cluster_9 1 IGKC 3.844 5.8159 0.9873
cluster_3 1 IGKC 3.4958 5.2017 0.9958
cluster_5 1 S100A8 3.3863 4.6398 1
cluster_12 1 S100A8 3.2903 4.721 1
cluster_8 1 CST3 3.2897 4.9162 1
cluster_1 1 DNASE1L3 2.9709 3.2903 0.9967
cluster_17 1 GZMB 2.6408 2.6804 1
cluster_14 1 KRT18 2.6015 2.6219 0.9167
cluster_4 1 HLA-DRA 2.5283 4.1303 0.9955
cluster_11 1 TM4SF1 2.5127 2.8022 0.9375
cluster_16 1 MS4A1 2.3591 2.3707 1
cluster_15 1 DNASE1L3 2.191 2.9272 1
cluster_2 1 FCN1 2.068 2.4768 0.9858
cluster_7 1 CCL4 1.4244 2.2494 0.9035
cluster_10 1 CCL5 1.4038 1.6615 0.7123
cluster_18 2 HBA2 6.6723 6.8244 1
cluster_13 2 IGHG4 5.8263 6.2738 1
cluster_19 2 TPSAB1 4.7058 4.7114 1
cluster_6 2 MARCO 3.8321 3.9452 0.9792
cluster_5 2 S100A9 3.2636 4.4894 1
cluster_3 2 JCHAIN 3.1684 3.7366 0.9833
cluster_8 2 CD74 3.1457 5.8646 1
cluster_9 2 JCHAIN 3.1377 3.9606 0.962
cluster_12 2 S100A9 2.9841 4.3863 1
cluster_1 2 FCN3 2.736 2.8708 0.99
cluster_14 2 KRT8 2.4549 2.4701 0.9722
cluster_11 2 EMP1 2.4321 2.5055 0.8281
cluster_4 2 CD74 2.3331 4.9447 1
cluster_15 2 FCN3 2.0111 2.5299 1
cluster_2 2 S100A4 1.9136 2.7567 0.9965
cluster_16 2 CD52 1.6925 2.5923 0.95
cluster_17 2 CD74 1.6293 4.4821 1
cluster_7 2 CCL5 1.3223 1.5559 0.7456
cluster_10 2 HIST1H4C 1.2338 1.8937 0.8356
cluster_18 3 HBA1 6.4958 6.6009 1
cluster_13 3 IGHG1 4.6236 5.3591 1

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
HCC-090-05-1H
Sample ID
HCC-090-05-1H
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Hepatocellular Cancer
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Hepatocellular Cancer; Normal
Tissue / Cell Source
Normal
Modality
scRNA-seq (GEXSCOPE)
Cell Count
2,399
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: HCC-090; Cancer type: Hepatocellular Cancer; Source: NCBI (GEO); Accession: GSE242889; Country: CHN; Sample type: Normal; Protocol: GEXSCOPE; Matrix: HCC-090-05-1H.counts.matrix.tsv.gz (4.42 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=2399; raw genes=21064; Leiden clusters=19; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Hepatocellular Cancer
cancer type short
HCC
library count
1
library sample ids
HCC-090-05-1H
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE242889; downloaded 2026-07-06
data accession
GSE242889
project id
HCC-090
sample type
Normal
country
CHN
data source
NCBI (GEO)
accession no
GSE242889
construction protocol
GEXSCOPE
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
HCC-090-05-1H.counts.matrix.tsv.gz
matrix file size bytes
4635670
matrix file size mb
4.42
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=2399; raw_genes=21064; leiden_clusters=19; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated