HSCC-130-02-1H
De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.
Donor-Level Analysis Results
Matrix-backed CancerSCEM donor analysis for HSCC-130-02-1H, generated 2026-07-09 12:54:49 +0800.
2,000Cells analyzed
19Clusters
22,332Expressed genes
5362Mean UMI
1751Mean genes
7.158Mean mito %
Gene Program Summary
| Program | Clusters | Mean Score | Max Score | Genes Used |
|---|---|---|---|---|
| B_plasma | 19 | 0.7747 | 2.2653 | 8 |
| Myeloid_APC | 19 | 0.3943 | 1.9537 | 9 |
| T_NK_cytotoxic | 19 | 0.3338 | 1.2351 | 10 |
| Proliferation | 19 | 0.2373 | 1.3965 | 7 |
| Checkpoint_exhaustion | 19 | 0.1596 | 0.3718 | 8 |
| Epithelial_tumor | 19 | 0.0882 | 1.1769 | 8 |
| Fibroblast_stroma | 19 | 0.0751 | 1.2827 | 8 |
| Endothelial | 19 | 0.0547 | 0.5202 | 7 |
Cluster QC
| Cluster | Cells | Mean UMI | Median Genes | Mean Mito % |
|---|---|---|---|---|
| cluster_1 | 278 | 3526.5971 | 1403 | 6.667 |
| cluster_2 | 278 | 3070.3525 | 1180 | 8.412 |
| cluster_3 | 238 | 3036.105 | 1193.5 | 6.7801 |
| cluster_4 | 231 | 8852.3247 | 2434 | 8.2462 |
| cluster_5 | 176 | 7075.2614 | 1170.5 | 4.6209 |
| cluster_6 | 135 | 8187.4 | 2507 | 7.431 |
| cluster_7 | 130 | 9186.9923 | 2988.5 | 6.7538 |
| cluster_8 | 115 | 3390.2783 | 1353 | 7.547 |
| cluster_9 | 95 | 4542.2316 | 1408 | 7.7324 |
| cluster_10 | 86 | 3453.1628 | 1362.5 | 6.8194 |
| cluster_11 | 68 | 7228.4559 | 2057.5 | 7.6392 |
| cluster_12 | 37 | 4647.7027 | 1719 | 6.3631 |
| cluster_13 | 34 | 4020.8235 | 1489 | 6.6397 |
| cluster_14 | 32 | 10544.5625 | 2400 | 6.7822 |
| cluster_15 | 19 | 4686.2632 | 1918 | 8.4246 |
| cluster_16 | 17 | 5395.1765 | 1512 | 7.215 |
| cluster_17 | 14 | 3382.8571 | 1439 | 8.6042 |
| cluster_18 | 11 | 6352.4545 | 2086 | 6.8595 |
| cluster_19 | 6 | 4022.3333 | 1553 | 7.7305 |
Top Cluster Marker Genes
| Cluster | Rank | Gene | Score | Mean Expr | Detect Fraction |
|---|---|---|---|---|---|
| cluster_19 | 1 | TPSAB1 | 4.8733 | 4.8779 | 1 |
| cluster_14 | 1 | SPP1 | 4.7806 | 5.0237 | 0.9062 |
| cluster_5 | 1 | IGKC | 3.9407 | 4.9924 | 0.9205 |
| cluster_15 | 1 | IGFBP7 | 3.6432 | 3.6876 | 1 |
| cluster_18 | 1 | CST3 | 3.3984 | 4.0728 | 1 |
| cluster_4 | 1 | CST3 | 3.3867 | 3.6886 | 0.9957 |
| cluster_16 | 1 | CCL22 | 3.0241 | 3.0771 | 0.8824 |
| cluster_12 | 1 | GZMB | 2.9771 | 3.0278 | 0.973 |
| cluster_7 | 1 | HSPB1 | 2.8325 | 3.5637 | 1 |
| cluster_6 | 1 | TUBA1B | 2.3038 | 3.3107 | 0.9926 |
| cluster_11 | 1 | GZMA | 2.1538 | 2.2262 | 0.9265 |
| cluster_9 | 1 | MS4A1 | 2.0833 | 2.517 | 1 |
| cluster_13 | 1 | PLIN2 | 1.5761 | 2.2253 | 0.9412 |
| cluster_8 | 1 | CCL5 | 1.52 | 1.7924 | 0.8 |
| cluster_2 | 1 | MS4A1 | 1.5006 | 1.8246 | 0.9712 |
| cluster_17 | 1 | MS4A1 | 1.2551 | 1.7789 | 1 |
| cluster_1 | 1 | IL32 | 1.212 | 1.7679 | 0.9712 |
| cluster_10 | 1 | ITM2A | 0.9117 | 1.3125 | 0.814 |
| cluster_3 | 1 | IL7R | 0.707 | 1.0563 | 0.7647 |
| cluster_19 | 2 | TPSB2 | 4.7791 | 4.7844 | 1 |
| cluster_14 | 2 | FTL | 3.4614 | 5.7187 | 1 |
| cluster_4 | 2 | HLA-DRA | 3.3348 | 4.8251 | 1 |
| cluster_5 | 2 | IGHG1 | 3.2959 | 3.6224 | 0.7557 |
| cluster_15 | 2 | SPARC | 3.2594 | 3.2735 | 0.9474 |
| cluster_7 | 2 | IFI27 | 2.8112 | 2.9668 | 0.9769 |
| cluster_18 | 2 | LYZ | 2.7424 | 3.1473 | 1 |
| cluster_16 | 2 | LAMP3 | 2.5969 | 2.7842 | 1 |
| cluster_6 | 2 | HMGB2 | 2.284 | 2.8445 | 0.9926 |
| cluster_11 | 2 | CCL5 | 2.1142 | 2.4021 | 0.8824 |
| cluster_12 | 2 | PLAC8 | 2.0148 | 2.3604 | 1 |
| cluster_9 | 2 | HLA-DRA | 1.4844 | 3.2893 | 1 |
| cluster_2 | 2 | HLA-DRA | 1.1606 | 2.8747 | 1 |
| cluster_13 | 2 | IL17RB | 1.1248 | 1.1565 | 0.6471 |
| cluster_1 | 2 | S100A4 | 1.12 | 2.2417 | 0.9604 |
| cluster_8 | 2 | GZMK | 0.8703 | 0.9546 | 0.687 |
| cluster_10 | 2 | TRAC | 0.8473 | 1.7183 | 0.9767 |
| cluster_17 | 2 | BANK1 | 0.7468 | 0.9969 | 0.8571 |
| cluster_3 | 2 | CD69 | 0.6285 | 2.2009 | 0.9286 |
| cluster_19 | 3 | CPA3 | 4.7129 | 4.7143 | 1 |
| cluster_14 | 3 | CTSB | 3.1714 | 3.8666 | 1 |
Primary Metadata
Core de-identified metadata fields migrated from the ImmuneAging donor manifest.
Donor ID
HSCC-130-02-1H
Sample ID
HSCC-130-02-1H
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Hypopharygeal Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Hypopharygeal Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (GEXSCOPE)
Cell Count
4,296
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: HSCC-130; Cancer type: Hypopharygeal Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE227156; Country: CHN; Sample type: Tumour; Protocol: GEXSCOPE; Matrix: HSCC-130-02-1H.counts.matrix.tsv.gz (9.01 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=4296; raw genes=23767; Leiden clusters=19; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv
Additional Clinical / Source Fields
Supplementary source metadata retained from the migrated manifest where available.
cancer type
Hypopharygeal Squamous Cell Carcinoma
cancer type short
HSCC
library count
1
library sample ids
HSCC-130-02-1H
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE227156; downloaded 2026-07-06
data accession
GSE227156
project id
HSCC-130
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE227156
construction protocol
GEXSCOPE
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
HSCC-130-02-1H.counts.matrix.tsv.gz
matrix file size bytes
9452033
matrix file size mb
9.01
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=4296; raw_genes=23767; leiden_clusters=19; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated