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LUSC-092-01-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for LUSC-092-01-1A, generated 2026-07-09 12:54:49 +0800.

1,999Cells analyzed
18Clusters
24,543Expressed genes
7052Mean UMI
1814Mean genes
1.436Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 18 0.7901 2.825 8
Myeloid_APC 18 0.5545 1.9258 9
T_NK_cytotoxic 18 0.3166 2.0609 10
Checkpoint_exhaustion 18 0.151 0.7469 8
Epithelial_tumor 18 0.1103 0.5658 8
Endothelial 18 0.0637 0.2052 7
Proliferation 18 0.0566 0.1919 7
Fibroblast_stroma 18 0.0293 0.0745 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 414 2343.7005 989.5 0.8962
cluster_2 397 1930.8816 817 0.9182
cluster_3 160 2448.35 1033.5 1.1596
cluster_4 146 11374.3288 3920 2.5328
cluster_5 129 12681.0388 3361 2.7331
cluster_6 120 31464.0167 4029 1.4267
cluster_7 109 2923.2202 1113 0.6768
cluster_8 100 1639.13 524 1.447
cluster_9 72 12579.1389 4005.5 2.1244
cluster_10 69 14968.1449 4102 2.3898
cluster_11 69 11520.913 3864 1.9323
cluster_12 48 12196.1667 3800 3.0206
cluster_13 46 3977.413 239.5 0.6978
cluster_14 43 2749.907 1128 0.8682
cluster_15 27 1639.3704 460 4.1485
cluster_16 26 1500.8077 794 0.614
cluster_17 20 34755.1 4424.5 1.4491
cluster_18 4 3755 1670.5 3.8953
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_17 1 IGLC2 7.7329 9.0431 1
cluster_13 1 HBB 6.802 6.9598 1
cluster_6 1 IGKC 4.6396 6.835 1
cluster_18 1 TPSB2 3.8988 3.9091 1
cluster_9 1 GNLY 3.632 3.7723 1
cluster_12 1 BANK1 3.3369 3.3567 1
cluster_5 1 LYZ 3.1922 3.4023 0.9225
cluster_10 1 RPL13 3.1371 4.4348 0.9565
cluster_4 1 CCL5 2.912 3.0847 0.9452
cluster_7 1 S100A8 2.4254 4.4838 1
cluster_11 1 SKAP1 2.3319 2.7272 1
cluster_15 1 PPBP 2.0328 2.0429 0.8519
cluster_3 1 CXCL8 1.6546 2.4481 0.925
cluster_1 1 S100A8 1.4575 3.3463 0.9444
cluster_14 1 S100A8 1.3607 3.5221 0.9535
cluster_16 1 HSPA5 1.322 1.8838 0.9615
cluster_8 1 S100A2 1.1936 1.6221 0.85
cluster_2 1 AQP9 1.034 2.1946 0.9597
cluster_17 2 IGHG3 6.7312 7.4567 1
cluster_13 2 HBA2 6.3169 6.4564 1
cluster_6 2 IGHG1 4.151 4.8332 0.925
cluster_9 2 NKG7 3.5432 3.7827 1
cluster_18 2 CPA3 3.5084 3.5129 1
cluster_12 2 CD74 3.3142 3.912 1
cluster_10 2 RPL10 3.1272 4.4494 0.971
cluster_5 2 VCAN 2.7936 2.8383 0.7907
cluster_4 2 FYN 2.451 2.8283 0.9863
cluster_11 2 FYN 2.3069 2.7836 1
cluster_7 2 S100A9 2.0307 4.1209 0.9908
cluster_15 2 GP1BB 1.8048 1.8133 0.8519
cluster_3 2 DOCK4 1.3709 2.1782 0.9688
cluster_14 2 NAMPT 1.264 3.7194 1
cluster_16 2 PTMA 1.2036 2.4233 1
cluster_1 2 NAMPT 1.1958 3.4308 1
cluster_2 2 NAMPT 1.032 3.3096 0.9975
cluster_8 2 KRT17 0.9736 1.138 0.69
cluster_17 3 IGLC3 5.9898 6.291 0.95
cluster_13 3 HBA1 5.4093 5.5041 1
cluster_6 3 JCHAIN 3.9371 4.1658 0.9667
cluster_9 3 CCL4 3.2396 3.6449 1

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
LUSC-092-01-1A
Sample ID
LUSC-092-01-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Lung Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Lung Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
6,540
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: LUSC-092; Cancer type: Lung Squamous Cell Carcinoma; Source: NCBI (SRA); Accession: PRJNA976462; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: LUSC-092-01-1A.counts.matrix.tsv.gz (15.71 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=6540; raw genes=28855; Leiden clusters=18; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Lung Squamous Cell Carcinoma
cancer type short
LUSC
library count
1
library sample ids
LUSC-092-01-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (SRA); accession=PRJNA976462; downloaded 2026-07-06
data accession
PRJNA976462
project id
LUSC-092
sample type
Tumour
country
CHN
data source
NCBI (SRA)
accession no
PRJNA976462
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
LUSC-092-01-1A.counts.matrix.tsv.gz
matrix file size bytes
16469046
matrix file size mb
15.71
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=6540; raw_genes=28855; leiden_clusters=18; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated