LUSC-092-08-1A
De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.
Donor-Level Analysis Results
Matrix-backed CancerSCEM donor analysis for LUSC-092-08-1A, generated 2026-07-09 12:54:49 +0800.
2,000Cells analyzed
10Clusters
15,620Expressed genes
913Mean genes
Gene Program Summary
| Program | Clusters | Mean Score | Max Score | Genes Used |
|---|---|---|---|---|
| Myeloid_APC | 10 | 0.4629 | 0.7636 | 9 |
| T_NK_cytotoxic | 10 | 0.2899 | 1.339 | 7 |
| B_plasma | 10 | 0.1566 | 0.2744 | 5 |
| Checkpoint_exhaustion | 10 | 0.1161 | 0.4626 | 8 |
| Epithelial_tumor | 10 | 0.0926 | 0.3982 | 6 |
| Proliferation | 10 | 0.0468 | 0.152 | 3 |
| Fibroblast_stroma | 10 | 0.0287 | 0.1293 | 7 |
| Endothelial | 10 | 0.0094 | 0.0215 | 4 |
Cluster QC
| Cluster | Cells | Mean UMI | Median Genes | Mean Mito % |
|---|---|---|---|---|
| cluster_9 | 285 | 571 | ||
| cluster_8 | 271 | 439 | ||
| cluster_2 | 237 | 2347 | ||
| cluster_10 | 235 | 543 | ||
| cluster_1 | 233 | 558 | ||
| cluster_6 | 215 | 533 | ||
| cluster_7 | 175 | 1405.6057 | 547 | 0 |
| cluster_3 | 149 | 1841 | ||
| cluster_5 | 111 | 773 | ||
| cluster_4 | 89 | 1817.8764 | 1015 | 0 |
Top Cluster Marker Genes
| Cluster | Rank | Gene | Score | Mean Expr | Detect Fraction |
|---|---|---|---|---|---|
| cluster_2 | 1 | RPS27 | 2.9718 | 3.8613 | 0.9831 |
| cluster_3 | 1 | FYN | 1.9699 | 2.5323 | 0.9933 |
| cluster_6 | 1 | S100A8 | 1.8344 | 3.1861 | 0.9953 |
| cluster_1 | 1 | NAMPT | 1.6413 | 3.3681 | 1 |
| cluster_10 | 1 | NAMPT | 1.6185 | 3.3463 | 1 |
| cluster_5 | 1 | DNAH12 | 1.1845 | 1.2019 | 0.8739 |
| cluster_4 | 1 | SDK1 | 1.1519 | 1.2386 | 0.8202 |
| cluster_9 | 1 | LYZ | 0.7851 | 1.0873 | 0.6982 |
| cluster_7 | 1 | GAPDH | 0.6764 | 1.2911 | 0.6914 |
| cluster_8 | 1 | HBB | 0.2795 | 0.3618 | 0.1882 |
| cluster_2 | 2 | EEF1A1 | 2.7325 | 3.7994 | 0.9916 |
| cluster_3 | 2 | MBNL1 | 1.8917 | 2.8749 | 0.9799 |
| cluster_1 | 2 | S100A8 | 1.4383 | 2.8196 | 0.9742 |
| cluster_6 | 2 | NAMPT | 1.427 | 3.1916 | 1 |
| cluster_10 | 2 | CXCL8 | 1.2425 | 1.7033 | 0.8298 |
| cluster_4 | 2 | CD9 | 1.1245 | 1.2445 | 0.8539 |
| cluster_5 | 2 | CFAP299 | 1.0464 | 1.0666 | 0.7748 |
| cluster_7 | 2 | CCL19 | 0.6571 | 0.707 | 0.2857 |
| cluster_9 | 2 | HLA-DRA | 0.6349 | 1.0055 | 0.614 |
| cluster_8 | 2 | IGKC | 0.2006 | 0.3888 | 0.2214 |
| cluster_2 | 3 | RPS18 | 2.6055 | 3.2556 | 0.9873 |
| cluster_3 | 3 | MALAT1 | 1.8637 | 5.571 | 1 |
| cluster_6 | 3 | S100A9 | 1.3094 | 2.4157 | 0.9953 |
| cluster_1 | 3 | G0S2 | 1.2693 | 1.9862 | 0.9442 |
| cluster_10 | 3 | G0S2 | 1.2121 | 1.9344 | 0.9447 |
| cluster_4 | 3 | ATF3 | 0.9994 | 1.1636 | 0.8315 |
| cluster_5 | 3 | SPAG16 | 0.9905 | 1.0309 | 0.8018 |
| cluster_9 | 3 | HLA-DRB1 | 0.5152 | 0.8804 | 0.6596 |
| cluster_7 | 3 | KRT5 | 0.498 | 0.541 | 0.28 |
| cluster_8 | 3 | GNLY | 0.0984 | 0.4602 | 0.4207 |
| cluster_2 | 4 | RPS12 | 2.5885 | 3.4344 | 0.9831 |
| cluster_3 | 4 | TNFAIP3 | 1.7157 | 2.3212 | 0.9262 |
| cluster_1 | 4 | SOD2 | 1.1833 | 2.2119 | 0.9828 |
| cluster_10 | 4 | S100A8 | 1.1736 | 2.5845 | 0.966 |
| cluster_6 | 4 | MNDA | 1.1188 | 1.8288 | 0.9767 |
| cluster_4 | 4 | S100A2 | 0.9944 | 1.081 | 0.6966 |
| cluster_5 | 4 | AGBL4 | 0.8958 | 0.9133 | 0.7297 |
| cluster_7 | 4 | FDCSP | 0.4812 | 0.5243 | 0.2686 |
| cluster_9 | 4 | CD74 | 0.4163 | 0.8561 | 0.6491 |
| cluster_8 | 4 | PPBP | 0.0883 | 0.1135 | 0.0701 |
Primary Metadata
Core de-identified metadata fields migrated from the ImmuneAging donor manifest.
Donor ID
LUSC-092-08-1A
Sample ID
LUSC-092-08-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Lung Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Lung Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
16,475
Analysis Status
Matrix available; UMAP generated by fallback sampled pipeline
UMAP Status
Ready
Metadata / Source Notes
Project ID: LUSC-092; Cancer type: Lung Squamous Cell Carcinoma; Source: NCBI (SRA); Accession: PRJNA976462; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: LUSC-092-08-1A.counts.matrix.tsv.gz (20.31 MB); Matrix integrity: gzip file ended before end-of-stream marker during UMAP generation; redownload required before UMAP can be generated.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv
Additional Clinical / Source Fields
Supplementary source metadata retained from the migrated manifest where available.
cancer type
Lung Squamous Cell Carcinoma
cancer type short
LUSC
library count
1
library sample ids
LUSC-092-08-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (SRA); accession=PRJNA976462; downloaded 2026-07-06
data accession
PRJNA976462
project id
LUSC-092
sample type
Tumour
country
CHN
data source
NCBI (SRA)
accession no
PRJNA976462
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix incomplete; redownload required
matrix file name
LUSC-092-08-1A.counts.matrix.tsv.gz
matrix file size bytes
21298945
matrix file size mb
20.31
umap coordinates url
umap summary url
umap pipeline
Fallback Python normalize_total/log1p/HVG/SVD/UMAP; sampled 3000/16475 cells; generated 2026-07-09
matrix integrity status
Gzip EOF/truncated during UMAP generation