Home / Human Immune Atlas / Dataset Donors / MPLC-068-06-1A

MPLC-068-06-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for MPLC-068-06-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
18Clusters
24,907Expressed genes
6782Mean UMI
2442Mean genes
3.076Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 18 0.5041 2.0323 8
T_NK_cytotoxic 18 0.4444 1.7146 10
Myeloid_APC 18 0.3733 1.5898 9
Epithelial_tumor 18 0.182 0.6117 8
Checkpoint_exhaustion 18 0.1704 0.4979 8
Fibroblast_stroma 18 0.0835 0.7514 8
Proliferation 18 0.0565 0.1097 7
Endothelial 18 0.0466 0.326 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 375 7132.3973 2545 2.5218
cluster_2 372 8261.6048 2867 2.6065
cluster_3 194 4748.3247 2122.5 3.8411
cluster_4 187 1259.7166 609 3.9662
cluster_5 174 9817.4943 3184.5 2.7605
cluster_6 148 7202.723 2689 3.2829
cluster_7 135 6613.7185 2554 3.2563
cluster_8 94 5894.5851 2606.5 3.5152
cluster_9 58 8568.9828 2941 3.7987
cluster_10 52 6964.6538 2583 3.2983
cluster_11 50 5145 1722.5 0.9288
cluster_12 44 5612.6818 1704.5 3.0575
cluster_13 31 8690.4839 2401 4.0825
cluster_14 23 5704.5217 1619 4.2415
cluster_16 19 12495.1579 3677 3.8823
cluster_15 19 8471.0526 3089 3.5467
cluster_17 13 769.8462 516 4.6959
cluster_18 12 22066.5833 2264.5 1.2008
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_16 1 TPSB2 5.1143 5.1737 1
cluster_18 1 IGLC3 4.0914 4.2345 0.6667
cluster_15 1 NKG7 3.1013 3.3105 1
cluster_9 1 BANK1 2.5401 2.5648 1
cluster_17 1 SCGB3A1 2.388 3.4819 1
cluster_13 1 LYZ 2.1792 2.6831 0.8065
cluster_11 1 IFI27 2.1612 2.5049 1
cluster_7 1 CCL4 1.5816 1.8802 0.9037
cluster_5 1 SH3BGRL3 1.4452 3.1598 0.9943
cluster_10 1 KLRB1 1.4395 2.277 0.9423
cluster_14 1 CALD1 1.4247 1.4478 0.6522
cluster_12 1 SFTPB 1.356 2.1154 0.8409
cluster_1 1 FOS 1.3132 3.183 1
cluster_8 1 LINC02694 1.2835 1.9254 0.9255
cluster_2 1 NR3C1 1.2107 2.2899 0.9758
cluster_6 1 AL136456.1 0.9874 1.3055 0.6419
cluster_3 1 TC2N 0.497 0.9851 0.7371
cluster_4 1 HBG2 0.3669 1.3366 0.9037
cluster_16 2 TPSAB1 4.7518 4.7723 1
cluster_18 2 JCHAIN 3.6551 3.7178 0.8333
cluster_15 2 GNLY 3.0829 3.0977 1
cluster_9 2 CD83 2.2015 2.8964 1
cluster_13 2 HLA-DRA 2.1288 3.374 1
cluster_11 2 SFTA2 1.8881 2.1037 0.94
cluster_17 2 SCGB3A2 1.5337 1.5995 0.7692
cluster_7 2 CCL5 1.5337 2.5252 0.9852
cluster_5 2 PLIN2 1.4224 2.0242 0.9368
cluster_14 2 IGFBP7 1.3699 1.4516 0.6522
cluster_10 2 CCL5 1.3376 2.3978 0.9808
cluster_12 2 SCGB1A1 1.2156 1.8923 0.6364
cluster_2 2 S100A4 1.1915 2.748 0.9866
cluster_1 2 IL7R 1.1238 2.0618 0.9467
cluster_6 2 IKZF2 0.8615 0.9398 0.6757
cluster_8 2 ITGAE 0.7924 1.3452 0.883
cluster_3 2 GIMAP7 0.4381 0.7991 0.6443
cluster_4 2 LYZ 0.3355 0.8418 0.7487
cluster_16 3 CPA3 3.6938 3.7045 1
cluster_18 3 IGHA1 3.5022 3.8274 0.8333
cluster_15 3 CCL5 2.1322 3.2069 1
cluster_9 3 HLA-DRA 2.1245 3.3411 1

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
MPLC-068-06-1A
Sample ID
MPLC-068-06-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Multiple Primary Lung Cancer
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Multiple Primary Lung Cancer; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
7,646
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: MPLC-068; Cancer type: Multiple Primary Lung Cancer; Source: NCBI (GEO); Accession: GSE200972; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: MPLC-068-06-1A.counts.matrix.tsv.gz (19.87 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=7646; raw genes=28623; Leiden clusters=18; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Multiple Primary Lung Cancer
cancer type short
MPLC
library count
1
library sample ids
MPLC-068-06-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE200972; downloaded 2026-07-06
data accession
GSE200972
project id
MPLC-068
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE200972
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
MPLC-068-06-1A.counts.matrix.tsv.gz
matrix file size bytes
20833770
matrix file size mb
19.87
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=7646; raw_genes=28623; leiden_clusters=18; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated