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MPLC-068-07-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for MPLC-068-07-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
19Clusters
27,356Expressed genes
5568Mean UMI
2164Mean genes
2.779Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
B_plasma 19 0.3724 2.0964 8
T_NK_cytotoxic 19 0.1693 0.8902 10
Epithelial_tumor 19 0.1679 0.9481 8
Myeloid_APC 19 0.1601 0.8458 9
Checkpoint_exhaustion 19 0.1443 0.6144 8
Proliferation 19 0.1128 1.0418 7
Endothelial 19 0.0255 0.0916 7
Fibroblast_stroma 19 0.0118 0.0527 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 464 5710.7069 2400.5 3.0541
cluster_2 265 6697.283 2739 2.4713
cluster_3 172 4074.6163 1950 3.0058
cluster_4 133 5693.6466 2348 3.0885
cluster_5 127 11980.5906 3926 3.4584
cluster_6 115 5778.3739 2421 2.4152
cluster_7 114 1163.1754 729.5 2.5632
cluster_8 103 3283.1845 949 2.0466
cluster_9 99 3522.4141 1666 2.7587
cluster_10 78 3700.7436 900.5 2.5379
cluster_11 74 13469.8108 3628.5 3.4476
cluster_12 70 4911.6857 1857 3.051
cluster_13 61 1928.6557 1235 2.9164
cluster_14 45 1069.6444 674 1.4339
cluster_15 32 2484.7812 1086.5 2.0237
cluster_16 21 13644 1715 1.342
cluster_17 12 5092 2537 3.6318
cluster_18 9 2332.1111 1299 0.8208
cluster_19 6 878 615.5 1.9819
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_16 1 IGKC 6.2166 6.5157 0.9524
cluster_15 1 IGKC 5.0031 5.2875 1
cluster_11 1 SFTPC 4.7492 6.6111 0.9865
cluster_5 1 SFTPC 4.253 6.0206 1
cluster_1 1 TPSB2 2.5475 3.5266 0.9957
cluster_2 1 TPSB2 2.4872 3.7278 1
cluster_12 1 HLA-DRA 2.4506 3.0025 0.9857
cluster_18 1 S100A2 2.4238 2.4816 0.8889
cluster_3 1 CCL5 2.3795 2.5069 0.9128
cluster_6 1 IL32 2.2428 2.6647 0.9217
cluster_17 1 HMGB2 1.7731 2.0166 0.9167
cluster_10 1 LYZ 1.6908 1.7574 0.7821
cluster_4 1 IL32 1.6164 2.0598 0.9023
cluster_13 1 SFTPC 1.5628 3.5528 1
cluster_19 1 SFTPA1 1.5324 2.5642 1
cluster_8 1 TXN 1.4996 2.1131 0.9126
cluster_9 1 CCL5 1.263 1.5325 0.7778
cluster_7 1 SFTPB 1.2467 2.1228 0.9825
cluster_14 1 RBFOX1 0.7115 0.7275 0.7778
cluster_16 2 JCHAIN 4.3565 4.4217 0.9048
cluster_11 2 SFTPB 4.3141 5.1017 1
cluster_5 2 SFTPB 3.9984 4.6917 1
cluster_15 2 IGHG3 3.2389 3.3067 1
cluster_1 2 CPA3 2.52 3.2934 0.9871
cluster_2 2 TPSAB1 2.2249 3.2153 0.9925
cluster_12 2 CD74 2.2083 3.0405 1
cluster_18 2 KRT6A 2.1577 2.2136 1
cluster_6 2 LTB 1.7934 2.046 0.8783
cluster_17 2 TUBA1B 1.735 2.0968 0.9167
cluster_10 2 APOE 1.5756 1.8606 0.7436
cluster_4 2 INPP4B 1.5417 1.7924 0.8722
cluster_3 2 NKG7 1.3761 1.433 0.8314
cluster_19 2 SFTPC 1.3634 3.397 1
cluster_13 2 SFTPA1 1.2592 2.2571 1
cluster_8 2 SPP1 1.2486 1.3906 0.5631
cluster_7 2 SFTPC 1.0575 3.0349 0.9912
cluster_9 2 THEMIS 1.0448 1.1685 0.798
cluster_14 2 NAALADL2 0.4629 0.6827 0.7333
cluster_11 3 SFTPA1 4.2945 5.1719 1
cluster_16 3 IGHG4 4.2189 4.3535 0.8571

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
MPLC-068-07-1A
Sample ID
MPLC-068-07-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Multiple Primary Lung Cancer
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Multiple Primary Lung Cancer; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
6,955
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: MPLC-068; Cancer type: Multiple Primary Lung Cancer; Source: NCBI (GEO); Accession: GSE200972; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: MPLC-068-07-1A.counts.matrix.tsv.gz (18.24 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=6955; raw genes=29957; Leiden clusters=19; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Multiple Primary Lung Cancer
cancer type short
MPLC
library count
1
library sample ids
MPLC-068-07-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE200972; downloaded 2026-07-06
data accession
GSE200972
project id
MPLC-068
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE200972
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
MPLC-068-07-1A.counts.matrix.tsv.gz
matrix file size bytes
19128810
matrix file size mb
18.24
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=6955; raw_genes=29957; leiden_clusters=19; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated