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NSCLC-007-02-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for NSCLC-007-02-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
14Clusters
19,772Expressed genes
2877Mean UMI
1318Mean genes
3.92Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
Epithelial_tumor 14 0.3769 0.9767 7
B_plasma 14 0.3332 1.6834 8
Fibroblast_stroma 14 0.1879 0.8949 8
Myeloid_APC 14 0.1877 0.7774 9
Proliferation 14 0.0951 0.235 7
Endothelial 14 0.0773 0.6814 7
T_NK_cytotoxic 14 0.0308 0.2255 10
Checkpoint_exhaustion 14 0.0136 0.0468 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 690 3624.7971 1569.5 4.5475
cluster_2 482 2812.8963 1229.5 4.4279
cluster_3 295 1678.9525 758 2.7176
cluster_4 98 2680.4184 1273 3.8184
cluster_5 94 3327.8723 1407.5 3.8079
cluster_6 70 5054.6857 1857 4.2207
cluster_7 50 1316.14 674 2.8438
cluster_8 48 2141.875 1068.5 2.9418
cluster_9 47 1254.0426 483 3.1577
cluster_10 45 1561.8222 922 2.7688
cluster_11 25 1758.72 817 3.3623
cluster_12 23 1700.5217 645 2.1183
cluster_13 23 3420.3478 545 1.159
cluster_14 10 1310 467 2.2459
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_13 1 IGHG4 3.49 4.3626 0.8696
cluster_14 1 TPSB2 2.875 2.9089 1
cluster_8 1 IGFBP7 2.4901 2.8792 0.9792
cluster_12 1 APOD 2.3522 2.5119 0.913
cluster_7 1 PLP1 2.0283 2.0728 0.94
cluster_9 1 CCL3 2.017 2.3688 0.9574
cluster_10 1 IGFBP7 1.558 1.9718 0.9556
cluster_3 1 APOC1 1.5514 2.093 0.8915
cluster_11 1 CLU 1.2244 1.3416 0.6
cluster_6 1 S100A6 1.0194 3.7897 1
cluster_1 1 S100A6 0.9084 3.4009 1
cluster_5 1 HSPA1A 0.6926 0.8776 0.7766
cluster_2 1 SEC61G 0.5715 2.5428 1
cluster_4 1 IL32 0.5329 1.0191 0.8163
cluster_13 2 IGHG1 3.4792 3.6896 0.7391
cluster_12 2 TIMP1 2.3412 3.2061 0.9565
cluster_8 2 CALD1 1.7717 1.8237 0.9375
cluster_14 2 TPSAB1 1.7694 1.7736 0.9
cluster_10 2 SPARC 1.459 1.6421 0.8667
cluster_3 2 CD74 1.4473 2.2506 0.9559
cluster_9 2 CCL4 1.42 1.6358 0.8723
cluster_7 2 PPP1R14A 1.2217 1.2859 0.88
cluster_6 2 SEC61G 0.973 3.048 1
cluster_1 2 MT-ND1 0.9055 2.9756 0.9971
cluster_11 2 PTGDS 0.8163 1.0077 0.64
cluster_5 2 S100A6 0.6614 3.4362 1
cluster_2 2 S100A6 0.4911 3.1787 1
cluster_4 2 CD52 0.451 0.5951 0.5714
cluster_13 3 IGKC 3.3335 4.3381 0.8261
cluster_12 3 MGP 2.3251 2.5267 1
cluster_8 3 NDUFA4L2 1.555 1.5977 0.9167
cluster_3 3 APOE 1.358 2.1224 0.878
cluster_7 3 PTGDS 1.1835 1.3555 0.86
cluster_10 3 CLDN5 1.101 1.1336 0.8
cluster_9 3 CD74 1.0701 2.0617 0.9787
cluster_14 3 CPA3 1.0669 1.0686 0.7
cluster_6 3 IFI27 0.9632 2.8166 1
cluster_1 3 IFI27 0.8772 2.4617 0.9928
cluster_11 3 MT3 0.7923 0.867 0.64
cluster_5 3 HSPA1B 0.6169 0.7389 0.7234

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
NSCLC-007-02-1A
Sample ID
NSCLC-007-02-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Non-small Cell Lung Cancer
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Non-small Cell Lung Cancer; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
9,595
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: NSCLC-007; Cancer type: Non-small Cell Lung Cancer; Source: NCBI (GEO); Accession: GSE143423; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: NSCLC-007-02-1A.counts.matrix.tsv.gz (14.82 MB); UMAP: Scanpy-generated donor-level UMAP preview, 14 Leiden clusters; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Non-small Cell Lung Cancer
cancer type short
NSCLC
library count
1
library sample ids
NSCLC-007-02-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE143423; downloaded 2026-07-06
data accession
GSE143423
project id
NSCLC-007
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE143423
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
NSCLC-007-02-1A.counts.matrix.tsv.gz
matrix file size bytes
15544841
matrix file size mb
14.82
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=9595; raw_genes=21220; leiden_clusters=14; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated