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OSCC-074-01-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

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Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for OSCC-074-01-1A, generated 2026-07-09 12:54:49 +0800.

2,000Cells analyzed
22Clusters
25,857Expressed genes
5562Mean UMI
2038Mean genes
5.694Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
CancerSCEM Deep Analysis Donor JSON UMAP Coordinates UMAP Summary
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
Fibroblast_stroma 22 0.7753 3.2152 8
Myeloid_APC 22 0.466 2.2571 9
Epithelial_tumor 22 0.3096 0.9808 8
B_plasma 22 0.2184 1.1282 8
Proliferation 22 0.1626 1.714 7
T_NK_cytotoxic 22 0.1293 0.6135 10
Checkpoint_exhaustion 22 0.1201 0.4328 8
Endothelial 22 0.0634 0.4466 7
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 341 901.7683 516 6.9345
cluster_2 208 3141.9567 1504.5 5.6451
cluster_3 192 3278.474 1570.5 5.7321
cluster_4 165 13077.2485 4178 5.56
cluster_5 143 6013.986 2301 5.6829
cluster_6 138 10865.8551 3774 5.4658
cluster_7 122 8855.0902 3248 5.8707
cluster_8 121 3830.7438 1907 5.0769
cluster_9 94 3607.1702 1051 3.7406
cluster_10 93 11684.4409 3454 5.5854
cluster_11 92 9181.7065 2833 4.8867
cluster_12 70 1351.1 534 5.3728
cluster_13 68 7691.6176 2087.5 5.533
cluster_14 56 2198.1786 705.5 5.6658
cluster_15 24 2040.625 895.5 5.9643
cluster_16 22 4005.6818 1426.5 5.923
cluster_17 18 1718.1667 641.5 5.7638
cluster_18 16 11758.6875 3356 5.3982
cluster_19 6 9296 3524.5 3.9218
cluster_20 5 570.2 371 6.5542
cluster_21 4 8961.75 3081.5 2.6313
cluster_22 2 4842 2079.5 6.6748
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_5 1 TPSB2 4.5241 4.5967 1
cluster_18 1 HLA-DRB1 3.9868 4.7677 1
cluster_10 1 HLA-DRA 3.8466 4.5377 0.9677
cluster_20 1 HBB 3.8108 3.831 1
cluster_4 1 COL1A1 3.771 5.0464 1
cluster_21 1 GZMB 3.4185 3.4908 1
cluster_11 1 HLA-DRA 3.3834 4.0977 0.9891
cluster_22 1 TPSB2 3.341 3.7337 1
cluster_7 1 IGFBP7 3.2565 4.183 1
cluster_19 1 HIST1H4C 3.2425 3.529 1
cluster_6 1 COL1A1 2.9359 4.3198 1
cluster_13 1 KRT14 2.4674 3.8012 0.9853
cluster_9 1 KRT14 2.1396 3.4566 1
cluster_12 1 CXCL8 2.0085 2.4751 0.9429
cluster_16 1 IGKC 1.9936 2.0363 0.5909
cluster_3 1 CCL5 1.6207 1.6703 0.8958
cluster_8 1 IL32 1.5599 1.9906 0.9256
cluster_17 1 DES 1.5282 1.5482 0.8889
cluster_14 1 HLA-DRA 1.4274 2.2574 0.9821
cluster_2 1 LTB 0.7208 0.937 0.649
cluster_15 1 RAMP2 0.6783 0.691 0.7083
cluster_1 1 KRT14 0.2449 1.6208 0.9589
cluster_18 2 HLA-DRA 3.9138 4.7524 1
cluster_10 2 HLA-DRB1 3.7581 4.3962 0.9785
cluster_4 2 COL3A1 3.3904 4.3659 1
cluster_5 2 TPSAB1 3.3267 3.3492 0.986
cluster_11 2 HLA-DRB1 3.1626 3.8299 0.9891
cluster_6 2 COL3A1 2.9089 3.9634 1
cluster_20 2 HBA2 2.8258 2.8407 1
cluster_7 2 CALD1 2.7421 3.4972 1
cluster_21 2 FCHSD2 2.6365 2.9041 1
cluster_19 2 HMGB2 2.4458 2.6078 1
cluster_13 2 CXCL14 2.3411 3.0274 1
cluster_9 2 S100A2 1.896 3.0779 0.9787
cluster_22 2 TPSAB1 1.8363 2.0948 1
cluster_12 2 NAMPT 1.5427 2.352 1
cluster_8 2 AL136456.1 1.3747 1.4631 0.7934
cluster_3 2 CCL4 1.1708 1.495 0.7292
cluster_14 2 HLA-DRB1 1.1523 1.9328 0.9464
cluster_17 2 TNNT3 1.1462 1.1565 0.8333

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
OSCC-074-01-1A
Sample ID
OSCC-074-01-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Oral Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Oral Squamous Cell Carcinoma; Tumour
Tissue / Cell Source
Tumour
Modality
scRNA-seq (10X Genomics)
Cell Count
7,867
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: OSCC-074; Cancer type: Oral Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE193766; Country: CHN; Sample type: Tumour; Protocol: 10X Genomics; Matrix: OSCC-074-01-1A.counts.matrix.tsv.gz (19.70 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=7867; raw genes=29847; Leiden clusters=22; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Oral Squamous Cell Carcinoma
cancer type short
OSCC
library count
1
library sample ids
OSCC-074-01-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE193766; downloaded 2026-07-06
data accession
GSE193766
project id
OSCC-074
sample type
Tumour
country
CHN
data source
NCBI (GEO)
accession no
GSE193766
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
OSCC-074-01-1A.counts.matrix.tsv.gz
matrix file size bytes
20659454
matrix file size mb
19.70
matrix download url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_matrix/OSCC-074-01-1A.counts.matrix.tsv.gz
umap coordinates url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/OSCC-074-01-1A.umap.tsv.gz
umap summary url
http://8.142.154.29/LACA/data/human_immune_atlas/cancerscem_2_umap/OSCC-074-01-1A.summary.json
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=7867; raw_genes=29847; leiden_clusters=22; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated