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OSCC-074-03-1A

De-identified Human Immune Atlas donor/sample detail for CancerSCEM 2.0. The record preserves available public metadata while avoiding direct identifiers.

Donor-Level Analysis Results

Matrix-backed CancerSCEM donor analysis for OSCC-074-03-1A, generated 2026-07-09 12:54:49 +0800.

1,998Cells analyzed
18Clusters
24,399Expressed genes
8360Mean UMI
2280Mean genes
3.44Mean mito %
Donor-level analysis panel
Cluster cell counts, cluster-by-program score heatmap, and top marker genes.
Gene Program Summary
Program Clusters Mean Score Max Score Genes Used
Myeloid_APC 18 0.4619 2.0252 9
B_plasma 18 0.4064 1.839 8
T_NK_cytotoxic 18 0.2466 0.8315 10
Checkpoint_exhaustion 18 0.1309 0.4317 8
Fibroblast_stroma 18 0.1074 1.1167 8
Endothelial 18 0.0658 0.656 7
Proliferation 18 0.0571 0.1872 7
Epithelial_tumor 18 0.0522 0.6604 8
Cluster QC
Cluster Cells Mean UMI Median Genes Mean Mito %
cluster_1 366 8258.1093 2262 3.7175
cluster_2 314 6652.7325 2184 4.2186
cluster_3 191 8829.1728 2416 3.4344
cluster_4 169 1737.4675 643 0.9721
cluster_5 166 14061.9398 2977 3.2415
cluster_6 148 8593.2432 2502 3.4003
cluster_7 122 8617.9344 2599.5 4.2272
cluster_8 93 15877.6667 3367 3.3975
cluster_9 89 8404.191 1832 3.3756
cluster_10 86 7118.4767 2215.5 3.9749
cluster_11 76 7617.6316 2325 3.1705
cluster_12 46 7472.8913 2444.5 4.3772
cluster_13 45 8157.0444 2616 3.3338
cluster_14 38 13191.0789 1586.5 2.3681
cluster_15 27 3173.3704 1184 3.7967
cluster_16 13 10433.4615 3063 4.2834
cluster_17 5 12870.2 3119 2.235
cluster_18 4 10218.25 1406 0.3796
Top Cluster Marker Genes
Cluster Rank Gene Score Mean Expr Detect Fraction
cluster_5 1 S100A9 4.1183 4.7092 0.988
cluster_14 1 IGLC2 4.115 4.3597 0.6842
cluster_18 1 KRT13 4.0671 4.072 0.75
cluster_8 1 HLA-DRA 4.056 4.8195 1
cluster_17 1 GZMB 3.3115 3.4301 1
cluster_4 1 S100A8 3.1769 3.7415 0.9704
cluster_15 1 CTSG 3.1674 3.2057 1
cluster_7 1 HLA-DRA 2.7039 3.491 0.9918
cluster_13 1 GNLY 2.472 2.5571 0.7556
cluster_9 1 DCN 2.4081 2.5259 0.9326
cluster_12 1 HLA-DRA 2.3757 3.2733 0.9783
cluster_16 1 IGFBP7 2.108 2.2515 0.8462
cluster_2 1 CCL5 1.8529 1.9544 0.9172
cluster_11 1 IKZF2 1.5323 1.6084 0.9474
cluster_6 1 RORA 1.3966 2.0326 0.973
cluster_1 1 CMSS1 1.3576 2.19 0.8798
cluster_3 1 FAAH2 1.0675 1.8202 0.7749
cluster_10 1 CD69 0.9514 1.8222 0.907
cluster_18 2 S100A8 4.0466 4.8718 1
cluster_14 2 JCHAIN 3.7491 3.8173 0.8684
cluster_5 2 LYZ 3.7392 4.0584 0.988
cluster_8 2 CD74 3.5186 4.4215 1
cluster_15 2 HPGD 3.1281 3.2047 1
cluster_17 2 FCHSD2 2.9664 3.3927 1
cluster_4 2 S100A9 2.4014 3.1312 0.9763
cluster_9 2 MT2A 2.3684 3.189 0.9213
cluster_7 2 CD74 2.2206 3.1517 0.9918
cluster_12 2 EBF1 1.9707 2.2114 0.9565
cluster_16 2 CALCRL 1.9507 2.0014 0.7692
cluster_13 2 NKG7 1.4064 1.6198 0.7111
cluster_11 2 LDLRAD4 1.2783 2.1957 0.9211
cluster_1 2 PITPNC1 1.2191 2.4958 0.9727
cluster_6 2 LDLRAD4 1.0897 1.975 0.9189
cluster_2 2 NKG7 1.0067 1.0936 0.7134
cluster_3 2 TSHZ2 0.9204 1.603 0.7277
cluster_10 2 FOS 0.7821 1.8222 0.8721
cluster_18 3 S100A9 3.7665 4.692 1
cluster_5 3 S100A8 3.6215 4.1539 0.988
cluster_8 3 CST3 3.5088 3.9543 0.9892
cluster_14 3 IGKC 3.0368 3.4169 0.6316

Primary Metadata

Core de-identified metadata fields migrated from the ImmuneAging donor manifest.

Donor ID
OSCC-074-03-1A
Sample ID
OSCC-074-03-1A
Dataset
CancerSCEM 2.0
Cohort
CancerSCEM 2.0 Chinese subset; Oral Squamous Cell Carcinoma
Age / Age Group
Pan-cancer Chinese cohort, per-donor ages not in CancerSCEM metadata
Sex
Not reported in public CancerSCEM metadata
Health Status
Oral Squamous Cell Carcinoma; Normal
Tissue / Cell Source
Normal
Modality
scRNA-seq (10X Genomics)
Cell Count
8,613
Analysis Status
Matrix available; UMAP generated
UMAP Status
Ready
Metadata / Source Notes
Project ID: OSCC-074; Cancer type: Oral Squamous Cell Carcinoma; Source: NCBI (GEO); Accession: GSE193766; Country: CHN; Sample type: Normal; Protocol: 10X Genomics; Matrix: OSCC-074-03-1A.counts.matrix.tsv.gz (22.48 MB); UMAP: Scanpy-generated donor-level UMAP preview; cells=8613; raw genes=27111; Leiden clusters=18; coordinates TSV and summary JSON are available online.; Age/sex not reported in public CancerSCEM metadata. Age source: CancerSCEM 2.0 database; 400 samples across 47 cancer types; donor-level age not included in download.csv

Additional Clinical / Source Fields

Supplementary source metadata retained from the migrated manifest where available.

cancer type
Oral Squamous Cell Carcinoma
cancer type short
OSCC
library count
1
library sample ids
OSCC-074-03-1A
source reference
CancerSCEM 2.0 metadata table; data source=NCBI (GEO); accession=GSE193766; downloaded 2026-07-06
data accession
GSE193766
project id
OSCC-074
sample type
Normal
country
CHN
data source
NCBI (GEO)
accession no
GSE193766
construction protocol
10X Genomics
transcriptome profile
Yes
metabolic profile
Yes
matrix status
Matrix available
matrix file name
OSCC-074-03-1A.counts.matrix.tsv.gz
matrix file size bytes
23568030
matrix file size mb
22.48
matrix download url
umap coordinates url
umap summary url
umap pipeline
Scanpy 1.9.8 normalize_total/log1p/HVG/PCA/neighbors/leiden/umap; cells=8613; raw_genes=27111; leiden_clusters=18; generated 2026-07-07
matrix integrity status
Gzip readable; UMAP generated